Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5VWU

Crystal structure of oxidized Aspergillus fumigatus UDP-galactopyranose mutase complexed with NADH

Replaces: 4GDD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0008767	molecular_function	UDP-galactopyranose mutase activity
A	0016853	molecular_function	isomerase activity
A	0071555	biological_process	cell wall organization
B	0000166	molecular_function	nucleotide binding
B	0008767	molecular_function	UDP-galactopyranose mutase activity
B	0016853	molecular_function	isomerase activity
B	0071555	biological_process	cell wall organization
C	0000166	molecular_function	nucleotide binding
C	0008767	molecular_function	UDP-galactopyranose mutase activity
C	0016853	molecular_function	isomerase activity
C	0071555	biological_process	cell wall organization
D	0000166	molecular_function	nucleotide binding
D	0008767	molecular_function	UDP-galactopyranose mutase activity
D	0016853	molecular_function	isomerase activity
D	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	28
Details	binding site for residue FAD A 601

Chain	Residue
A	GLY14
A	GLY61
A	GLY62
A	HIS63
A	GLY240
A	VAL242
A	MET269
A	THR295
A	ARG327
A	GLU373
A	GLY418
A	GLY16
A	TYR419
A	GLY446
A	ARG447
A	GLY456
A	ASN457
A	GLN458
A	SER461
A	NAI602
A	HOH702
A	PRO17
A	THR18
A	ASP38
A	SER39
A	GLY45
A	LEU46
A	ALA47

site_id	AC2
Number of Residues	13
Details	binding site for residue NAI A 602

Chain	Residue
A	ILE65
A	HIS68
A	ARG91
A	SER93
A	TYR317
A	ARG327
A	TYR419
A	ARG447
A	TYR453
A	ASN457
A	HIS460
A	FAD601
A	SO4604

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 603

Chain	Residue
A	THR88
A	HIS89
A	GLN90
A	LYS313

site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 A 604

Chain	Residue
A	TYR317
A	ARG327
A	NAI602

site_id	AC5
Number of Residues	28
Details	binding site for residue FAD B 601

Chain	Residue
B	GLY14
B	GLY16
B	PRO17
B	THR18
B	ASP38
B	SER39
B	GLY45
B	LEU46
B	ALA47
B	GLY61
B	GLY62
B	HIS63
B	GLY240
B	VAL242
B	MET269
B	THR295
B	ARG327
B	GLU373
B	GLY418
B	TYR419
B	GLY446
B	ARG447
B	GLY456
B	ASN457
B	GLN458
B	SER461
B	NAI602
B	HOH703

site_id	AC6
Number of Residues	13
Details	binding site for residue NAI B 602

Chain	Residue
B	ILE65
B	HIS68
B	ARG91
B	SER93
B	TYR104
B	TYR317
B	TYR419
B	ARG447
B	TYR453
B	ASN457
B	HIS460
B	FAD601
B	SO4605

site_id	AC7
Number of Residues	2
Details	binding site for residue SO4 B 603

Chain	Residue
B	LYS70
B	ARG496

site_id	AC8
Number of Residues	3
Details	binding site for residue SO4 B 604

Chain	Residue
B	HIS89
B	GLN90
B	LYS313

site_id	AC9
Number of Residues	4
Details	binding site for residue SO4 B 605

Chain	Residue
B	TRP315
B	TYR317
B	ARG327
B	NAI602

site_id	AD1
Number of Residues	26
Details	binding site for residue FAD C 601

Chain	Residue
C	GLY16
C	PRO17
C	THR18
C	ASP38
C	SER39
C	GLY45
C	LEU46
C	ALA47
C	VAL60
C	GLY61
C	GLY62
C	HIS63
C	GLY240
C	VAL242
C	THR268
C	MET269
C	HIS417
C	GLY418
C	GLY446
C	ARG447
C	GLY456
C	ASN457
C	GLN458
C	SER461
C	SO4605
C	GLY14

site_id	AD2
Number of Residues	4
Details	binding site for residue SO4 C 602

Chain	Residue
C	PRO307
C	GLU308
C	ARG309
C	LYS402

site_id	AD3
Number of Residues	2
Details	binding site for residue SO4 C 603

Chain	Residue
C	PRO114
C	LYS115

site_id	AD4
Number of Residues	2
Details	binding site for residue SO4 C 604

Chain	Residue
C	HIS89
C	GLN90

site_id	AD5
Number of Residues	6
Details	binding site for residue SO4 C 605

Chain	Residue
C	HIS63
C	TYR419
C	ARG447
C	TYR453
C	ASN457
C	FAD601

site_id	AD6
Number of Residues	26
Details	binding site for residue FAD D 601

Chain	Residue
D	GLY14
D	GLY16
D	PRO17
D	THR18
D	ASP38
D	SER39
D	GLY45
D	LEU46
D	ALA47
D	VAL60
D	GLY61
D	GLY62
D	HIS63
D	GLY240
D	VAL242
D	THR268
D	MET269
D	HIS417
D	GLY418
D	GLY446
D	ARG447
D	GLY456
D	ASN457
D	GLN458
D	SER461
D	SO4605

site_id	AD7
Number of Residues	2
Details	binding site for residue SO4 D 602

Chain	Residue
D	THR137
D	LYS138

site_id	AD8
Number of Residues	4
Details	binding site for residue SO4 D 603

Chain	Residue
D	PRO307
D	GLU308
D	ARG309
D	LYS402

site_id	AD9
Number of Residues	1
Details	binding site for residue SO4 D 604

Chain	Residue
D	LYS115

site_id	AE1
Number of Residues	6
Details	binding site for residue SO4 D 605

Chain	Residue
D	HIS63
D	TYR419
D	ARG447
D	TYR453
D	ASN457
D	FAD601

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	26
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23036087","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VWT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	30
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22294687","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22334662","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3UKH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)