Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue HEM A 501 |
| Chain | Residue |
| A | TRP180 |
| A | TRP449 |
| A | PHE475 |
| A | TYR477 |
| A | H4B502 |
| A | P94503 |
| A | HOH602 |
| A | ALA183 |
| A | CYS186 |
| A | SER228 |
| A | PHE355 |
| A | SER356 |
| A | TRP358 |
| A | MET360 |
| A | GLU363 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue H4B A 502 |
| Chain | Residue |
| A | SER104 |
| A | ARG367 |
| A | ALA448 |
| A | TRP449 |
| A | HEM501 |
| A | GOL506 |
| A | HOH602 |
| B | TRP447 |
| B | PHE462 |
| B | HOH602 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue P94 A 503 |
| Chain | Residue |
| A | VAL106 |
| A | LEU107 |
| A | VAL338 |
| A | TRP358 |
| A | GLU363 |
| A | TRP449 |
| A | TYR477 |
| A | HEM501 |
| B | TRP76 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 504 |
| Chain | Residue |
| A | TRP358 |
| A | SER428 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 505 |
| Chain | Residue |
| A | ARG252 |
| A | ASN368 |
| A | ARG374 |
| A | HOH632 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 506 |
| Chain | Residue |
| A | VAL106 |
| A | ARG367 |
| A | HIS373 |
| A | H4B502 |
| B | TRP76 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 507 |
| Chain | Residue |
| A | CYS96 |
| A | CYS101 |
| B | CYS96 |
| B | CYS101 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | binding site for residue HEM B 501 |
| Chain | Residue |
| B | TRP180 |
| B | ARG185 |
| B | CYS186 |
| B | SER228 |
| B | PHE355 |
| B | SER356 |
| B | TRP358 |
| B | GLU363 |
| B | TRP449 |
| B | TYR477 |
| B | H4B502 |
| B | P94503 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue H4B B 502 |
| Chain | Residue |
| A | TRP447 |
| A | PHE462 |
| A | GLU465 |
| B | SER104 |
| B | ARG367 |
| B | ALA448 |
| B | TRP449 |
| B | HEM501 |
| B | GOL506 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue P94 B 503 |
| Chain | Residue |
| A | TRP76 |
| B | LEU107 |
| B | VAL338 |
| B | TRP358 |
| B | GLU363 |
| B | TRP449 |
| B | TYR477 |
| B | HEM501 |
| B | GOL506 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 504 |
| Chain | Residue |
| B | TRP358 |
| B | VAL420 |
| B | SER428 |
| B | HOH628 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 505 |
| Chain | Residue |
| B | GLN249 |
| B | ARG252 |
| B | ASN368 |
| B | ARG374 |
| B | HOH613 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 506 |
| Chain | Residue |
| B | VAL106 |
| B | ARG367 |
| B | HIS373 |
| B | H4B502 |
| B | P94503 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG185-TRP192 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | CYS96 | |
| A | CYS101 | |
| B | CYS96 | |
| B | CYS101 | |
| Chain | Residue | Details |
| A | SER104 | |
| A | TYR477 | |
| B | SER104 | |
| B | GLN249 | |
| B | TRP358 | |
| B | TYR359 | |
| B | GLU363 | |
| B | ASN368 | |
| B | ALA448 | |
| B | TRP449 | |
| B | PHE462 | |
| A | GLN249 | |
| B | TYR477 | |
| A | TRP358 | |
| A | TYR359 | |
| A | GLU363 | |
| A | ASN368 | |
| A | ALA448 | |
| A | TRP449 | |
| A | PHE462 | |
| Chain | Residue | Details |
| A | CYS186 | |
| B | CYS186 | |
| Chain | Residue | Details |
| A | SER116 | |
| B | SER116 | |
