Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue HEM A 801 |
| Chain | Residue |
| A | TRP414 |
| A | PHE709 |
| A | TYR711 |
| A | H4B802 |
| A | XH8803 |
| A | HOH923 |
| A | HOH929 |
| A | HOH968 |
| A | ARG419 |
| A | CYS420 |
| A | PHE589 |
| A | SER590 |
| A | GLY591 |
| A | TRP592 |
| A | GLU597 |
| A | TRP683 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue H4B A 802 |
| Chain | Residue |
| A | SER339 |
| A | ARG601 |
| A | VAL682 |
| A | TRP683 |
| A | HEM801 |
| A | HOH918 |
| A | HOH921 |
| A | HOH968 |
| A | HOH1008 |
| A | HOH1028 |
| B | TRP681 |
| B | PHE696 |
| B | HIS697 |
| B | GLN698 |
| B | GLU699 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue XH8 A 803 |
| Chain | Residue |
| A | HIS342 |
| A | PRO570 |
| A | VAL572 |
| A | TRP592 |
| A | GLU597 |
| A | HEM801 |
| A | HOH1117 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 804 |
| Chain | Residue |
| A | CYS331 |
| A | CYS336 |
| B | CYS331 |
| B | CYS336 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | binding site for residue HEM B 801 |
| Chain | Residue |
| B | TRP414 |
| B | ARG419 |
| B | CYS420 |
| B | SER462 |
| B | PHE589 |
| B | SER590 |
| B | GLY591 |
| B | TRP592 |
| B | GLU597 |
| B | PHE709 |
| B | TYR711 |
| B | H4B802 |
| B | XH8803 |
| B | HOH921 |
| B | HOH930 |
| B | HOH937 |
| B | HOH1011 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | binding site for residue H4B B 802 |
| Chain | Residue |
| A | TRP681 |
| A | PHE696 |
| A | HIS697 |
| A | GLN698 |
| A | GLU699 |
| B | SER339 |
| B | ARG601 |
| B | VAL682 |
| B | TRP683 |
| B | HEM801 |
| B | HOH921 |
| B | HOH947 |
| B | HOH971 |
| B | HOH981 |
| B | HOH987 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue XH8 B 803 |
| Chain | Residue |
| A | TRP311 |
| B | MET341 |
| B | HIS342 |
| B | VAL572 |
| B | TRP592 |
| B | GLU597 |
| B | HEM801 |
| B | HOH1011 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG419-TRP426 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER339 | |
| B | SER339 | |
| B | GLN483 | |
| B | TRP592 | |
| B | TYR593 | |
| B | GLU597 | |
| B | VAL682 | |
| B | TRP683 | |
| B | PHE696 | |
| B | TYR711 | |
| A | GLN483 | |
| A | TRP592 | |
| A | TYR593 | |
| A | GLU597 | |
| A | VAL682 | |
| A | TRP683 | |
| A | PHE696 | |
| A | TYR711 | |
| Chain | Residue | Details |
| A | CYS420 | |
| B | CYS420 | |
