5VSQ
ABA-mimicking ligand AMF2beta in complex with ABA receptor PYL2 and PP2C HAB1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| A | 0010427 | molecular_function | abscisic acid binding |
| A | 0016020 | cellular_component | membrane |
| A | 0038023 | molecular_function | signaling receptor activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0062049 | cellular_component | protein phosphatase inhibitor complex |
| B | 0004722 | molecular_function | protein serine/threonine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0043169 | molecular_function | cation binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue A2V A 300 |
| Chain | Residue |
| A | LYS64 |
| A | PHE165 |
| A | VAL169 |
| A | HOH411 |
| A | VAL67 |
| A | ARG83 |
| A | ALA93 |
| A | GLU98 |
| A | VAL114 |
| A | HIS119 |
| A | LEU121 |
| A | TYR124 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 601 |
| Chain | Residue |
| B | ASP243 |
| B | ASP346 |
| B | SER347 |
| B | SER431 |
| B | ASP432 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 602 |
| Chain | Residue |
| B | ASP243 |
| B | GLY244 |
| B | MG603 |
| B | HOH714 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 603 |
| Chain | Residue |
| B | ASP243 |
| B | ASP432 |
| B | ASP492 |
| B | MG602 |
| B | HOH711 |
Functional Information from PROSITE/UniProt
| site_id | PS01032 |
| Number of Residues | 9 |
| Details | PPM_1 PPM-type phosphatase domain signature. FFGVYDGHG |
| Chain | Residue | Details |
| B | PHE238-GLY246 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 154 |
| Details | Region: {"description":"START-like"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Motif: {"description":"Gate loop","evidences":[{"source":"PubMed","id":"19898420","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Motif: {"description":"Latch loop","evidences":[{"source":"PubMed","id":"19898420","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 13 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19893533","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19898420","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Involved in interactions with PP2Cs","evidences":[{"source":"UniProtKB","id":"O49686","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Involved in ABA binding","evidences":[{"source":"UniProtKB","id":"Q84MC7","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21658606","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3NMT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QN1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RT0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZVU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LA7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LGA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WVO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19898420","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3KB3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Site: {"description":"Lock"} |
| Chain | Residue | Details |
