5VRK

Crystal structure of SsoPox AsA6 mutant (F46L-C258A-W263M-I280T) - open form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004063	molecular_function	aryldialkylphosphatase activity
A	0008270	molecular_function	zinc ion binding
A	0009056	biological_process	catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0046872	molecular_function	metal ion binding
B	0004063	molecular_function	aryldialkylphosphatase activity
B	0008270	molecular_function	zinc ion binding
B	0009056	biological_process	catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016788	molecular_function	hydrolase activity, acting on ester bonds
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue FE2 A 401

Chain	Residue
A	HIS22
A	HIS24
A	KCX137
A	ASP256
A	CO402
A	EDO407
A	HOH516

---

site_id	AC2
Number of Residues	6
Details	binding site for residue CO A 402

Chain	Residue
A	HIS199
A	FE2401
A	EDO407
A	HOH516
A	KCX137
A	HIS170

---

site_id	AC3
Number of Residues	8
Details	binding site for residue GOL A 403

Chain	Residue
A	ASN160
A	LYS161
A	LYS164
A	GLY189
A	VAL190
A	ASP191
A	LYS194
A	HOH531

---

site_id	AC4
Number of Residues	6
Details	binding site for residue EDO A 404

Chain	Residue
A	LYS161
A	GLU162
A	LYS164
A	HOH754
B	GLU162
B	LYS164

---

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL A 405

Chain	Residue
A	ASN172
A	ALA173
A	ASP202
A	ARG223
A	PHE229
A	HOH536
A	HOH544

---

site_id	AC6
Number of Residues	6
Details	binding site for residue GOL A 406

Chain	Residue
A	ARG77
A	GLU80
A	THR129
A	HOH598
A	HOH735
B	ARG154

---

site_id	AC7
Number of Residues	8
Details	binding site for residue EDO A 407

Chain	Residue
A	HIS24
A	TYR97
A	HIS170
A	ARG223
A	FE2401
A	CO402
A	HOH516
A	HOH519

---

site_id	AC8
Number of Residues	7
Details	binding site for residue FE2 B 401

Chain	Residue
B	HIS22
B	HIS24
B	KCX137
B	ASP256
B	CO402
B	EDO408
B	HOH510

---

site_id	AC9
Number of Residues	6
Details	binding site for residue CO B 402

Chain	Residue
B	KCX137
B	HIS170
B	HIS199
B	FE2401
B	EDO408
B	HOH510

---

site_id	AD1
Number of Residues	7
Details	binding site for residue GOL B 403

Chain	Residue
B	ASN172
B	ALA173
B	HIS174
B	ASP202
B	PHE229
B	HOH528
B	HOH624

---

site_id	AD2
Number of Residues	5
Details	binding site for residue EDO B 404

Chain	Residue
B	ALA173
B	HIS174
B	ASN175
B	ASN176
B	TYR208

---

site_id	AD3
Number of Residues	11
Details	binding site for residue GOL B 405

Chain	Residue
B	LEU39
B	TYR40
B	GLU45
B	THR260
B	ILE261
B	ASP262
B	HOH504
B	HOH508
B	HOH564
B	HOH579
B	HOH621

---

site_id	AD4
Number of Residues	5
Details	binding site for residue GOL B 406

Chain	Residue
B	ALA213
B	ASP214
B	TYR247
B	ASP249
B	LYS250

---

site_id	AD5
Number of Residues	7
Details	binding site for residue GOL B 407

Chain	Residue
B	ASN160
B	LYS164
B	GLY189
B	VAL190
B	ASP191
B	LYS194
B	HOH567

---

site_id	AD6
Number of Residues	8
Details	binding site for residue EDO B 408

Chain	Residue
B	ARG223
B	FE2401
B	CO402
B	HOH510
B	HOH608
B	HIS24
B	TYR97
B	HIS170

---

Functional Information from PROSITE/UniProt

site_id	PS01322
Number of Residues	9
Details	PHOSPHOTRIESTERASE_1 Phosphotriesterase family signature 1. GfTLiHEHL

Chain	Residue	Details
A	GLY17-LEU25

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18486146","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VC7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KER","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KF1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"description":"via carbamate group","evidences":[{"source":"PubMed","id":"18486146","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VC7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KER","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KF1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00679","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18486146","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2VC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2VC7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3UF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KER","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KEZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4KF1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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