5VNX
Crystal structure of an 8-amino-7-oxononanoate synthase from Burkholderia multivorans with a potential glycine-PLP-Lys242 cyclized intermediate or byproduct
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008710 | molecular_function | 8-amino-7-oxononanoate synthase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009102 | biological_process | biotin biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0008710 | molecular_function | 8-amino-7-oxononanoate synthase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009102 | biological_process | biotin biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0008710 | molecular_function | 8-amino-7-oxononanoate synthase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009102 | biological_process | biotin biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue BEN A 601 |
| Chain | Residue |
| A | ARG21 |
| A | ILE354 |
| A | ARG355 |
| A | THR358 |
| A | HOH802 |
| B | SER76 |
| B | ILE269 |
| B | HOH832 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue BEN A 602 |
| Chain | Residue |
| A | ARG297 |
| A | ALA372 |
| A | ALA296 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 603 |
| Chain | Residue |
| A | GLY291 |
| A | ASP292 |
| A | GLU293 |
| A | HOH801 |
| A | HOH1064 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | LEU286 |
| A | ALA290 |
| A | HOH825 |
| A | HOH833 |
| A | HOH920 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 605 |
| Chain | Residue |
| A | GLY125 |
| A | LYS126 |
| A | ASP127 |
| A | ALA128 |
| A | THR173 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 606 |
| Chain | Residue |
| A | HIS156 |
| A | ASP185 |
| A | ASP187 |
| A | VAL320 |
| A | HOH806 |
| A | HOH886 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue BEN B 601 |
| Chain | Residue |
| A | SER76 |
| A | LEU79 |
| A | HOH846 |
| B | ARG21 |
| B | ILE354 |
| B | ARG355 |
| B | THR358 |
| B | HOH720 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue BEN B 602 |
| Chain | Residue |
| B | ALA296 |
| B | ARG297 |
| B | ALA372 |
| B | HOH846 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 603 |
| Chain | Residue |
| B | GLY291 |
| B | ASP292 |
| B | GLU293 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 604 |
| Chain | Residue |
| B | ASP295 |
| B | ALA296 |
| B | HOH746 |
| B | HOH870 |
| B | HOH1100 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue BEN C 601 |
| Chain | Residue |
| C | ARG21 |
| C | SER76 |
| C | LEU79 |
| C | ILE269 |
| C | ILE354 |
| C | ARG355 |
| C | THR358 |
| C | HOH753 |
| C | HOH822 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 C 602 |
| Chain | Residue |
| C | ARG23 |
| C | ARG105 |
| C | HOH706 |
| C | HOH711 |
| C | HOH776 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 603 |
| Chain | Residue |
| C | ARG68 |
| C | LYS287 |
| C | HOH772 |
| C | HOH923 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 604 |
| Chain | Residue |
| C | THR25 |
| C | ARG84 |
| C | ALA87 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 605 |
| Chain | Residue |
| C | ARG264 |
| C | HOH725 |
| C | HOH935 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 606 |
| Chain | Residue |
| C | ASP292 |
| C | HOH736 |
| C | HOH803 |
| C | HOH1063 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 21 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01693 |
| Chain | Residue | Details |
| A | ARG21 | |
| B | HIS137 | |
| B | SER183 | |
| B | HIS211 | |
| B | THR239 | |
| B | THR358 | |
| C | ARG21 | |
| C | GLY112 | |
| C | HIS137 | |
| C | SER183 | |
| C | HIS211 | |
| A | GLY112 | |
| C | THR239 | |
| C | THR358 | |
| A | HIS137 | |
| A | SER183 | |
| A | HIS211 | |
| A | THR239 | |
| A | THR358 | |
| B | ARG21 | |
| B | GLY112 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000255|HAMAP-Rule:MF_01693 |
| Chain | Residue | Details |
| A | 9EV242 | |
| B | 9EV242 | |
| C | 9EV242 |
