5VK4
Crystal structure of a phosphoribosylformylglycinamidine cyclo-ligase from Neisseria gonorrhoeae bound to AMPPNP and magnesium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004637 | molecular_function | phosphoribosylamine-glycine ligase activity |
| A | 0004641 | molecular_function | phosphoribosylformylglycinamidine cyclo-ligase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0046084 | biological_process | adenine biosynthetic process |
| B | 0004637 | molecular_function | phosphoribosylamine-glycine ligase activity |
| B | 0004641 | molecular_function | phosphoribosylformylglycinamidine cyclo-ligase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| B | 0046084 | biological_process | adenine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue ANP A 401 |
| Chain | Residue |
| A | VAL21 |
| B | THR247 |
| A | ASP105 |
| A | ILE121 |
| A | GLY137 |
| A | GLY138 |
| A | GLU139 |
| A | THR140 |
| A | HOH501 |
| B | ASP63 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | ASP63 |
| A | MET88 |
| A | ASP92 |
| B | ANP401 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for residue ANP B 401 |
| Chain | Residue |
| A | ASP63 |
| A | ASP92 |
| A | THR247 |
| A | ARG257 |
| A | MG402 |
| B | VAL21 |
| B | GLY41 |
| B | GLY42 |
| B | ASP105 |
| B | ILE121 |
| B | GLY137 |
| B | GLY138 |
| B | GLU139 |
| B | THR140 |
| B | MG402 |
| B | HOH501 |
| B | HOH502 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue MG B 402 |
| Chain | Residue |
| B | GLU139 |
| B | THR140 |
| B | ANP401 |
