5VK4
Crystal structure of a phosphoribosylformylglycinamidine cyclo-ligase from Neisseria gonorrhoeae bound to AMPPNP and magnesium
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004641 | molecular_function | phosphoribosylformylglycinamidine cyclo-ligase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0006164 | biological_process | purine nucleotide biosynthetic process |
A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
A | 0016874 | molecular_function | ligase activity |
B | 0004641 | molecular_function | phosphoribosylformylglycinamidine cyclo-ligase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0006164 | biological_process | purine nucleotide biosynthetic process |
B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
B | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | binding site for residue ANP A 401 |
Chain | Residue |
A | VAL21 |
B | THR247 |
A | ASP105 |
A | ILE121 |
A | GLY137 |
A | GLY138 |
A | GLU139 |
A | THR140 |
A | HOH501 |
B | ASP63 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue MG A 402 |
Chain | Residue |
A | ASP63 |
A | MET88 |
A | ASP92 |
B | ANP401 |
site_id | AC3 |
Number of Residues | 17 |
Details | binding site for residue ANP B 401 |
Chain | Residue |
A | ASP63 |
A | ASP92 |
A | THR247 |
A | ARG257 |
A | MG402 |
B | VAL21 |
B | GLY41 |
B | GLY42 |
B | ASP105 |
B | ILE121 |
B | GLY137 |
B | GLY138 |
B | GLU139 |
B | THR140 |
B | MG402 |
B | HOH501 |
B | HOH502 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue MG B 402 |
Chain | Residue |
B | GLU139 |
B | THR140 |
B | ANP401 |