5VJY

Crystal Structure of dUTP pyrophosphatase protein, from Naegleria fowleri

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004170	molecular_function	dUTP diphosphatase activity
A	0006226	biological_process	dUMP biosynthetic process
A	0009117	biological_process	nucleotide metabolic process
A	0016787	molecular_function	hydrolase activity
A	0046081	biological_process	dUTP catabolic process
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0004170	molecular_function	dUTP diphosphatase activity
B	0006226	biological_process	dUMP biosynthetic process
B	0009117	biological_process	nucleotide metabolic process
B	0016787	molecular_function	hydrolase activity
B	0046081	biological_process	dUTP catabolic process
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0004170	molecular_function	dUTP diphosphatase activity
C	0006226	biological_process	dUMP biosynthetic process
C	0009117	biological_process	nucleotide metabolic process
C	0016787	molecular_function	hydrolase activity
C	0046081	biological_process	dUTP catabolic process
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0004170	molecular_function	dUTP diphosphatase activity
D	0006226	biological_process	dUMP biosynthetic process
D	0009117	biological_process	nucleotide metabolic process
D	0016787	molecular_function	hydrolase activity
D	0046081	biological_process	dUTP catabolic process
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0004170	molecular_function	dUTP diphosphatase activity
E	0006226	biological_process	dUMP biosynthetic process
E	0009117	biological_process	nucleotide metabolic process
E	0016787	molecular_function	hydrolase activity
E	0046081	biological_process	dUTP catabolic process
E	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue BTB A 201

Chain	Residue
A	SER67
A	ALA79
A	GLY80
A	VAL81
A	TYR86
A	ASN89
A	GLY91
A	HOH323
A	HOH342

---

site_id	AC2
Number of Residues	6
Details	binding site for residue EDO A 202

Chain	Residue
A	TYR35
A	LYS48
A	ASP50
A	ASN89
A	HOH311
C	ASP122

---

site_id	AC3
Number of Residues	10
Details	binding site for residue BTB B 200

Chain	Residue
B	ALA79
B	GLY80
B	VAL81
B	TYR86
B	ASN89
B	GLY91
B	HOH310
B	HOH318
B	HOH327
D	SER67

---

site_id	AC4
Number of Residues	9
Details	binding site for residue BTB C 200

Chain	Residue
B	SER67
C	GLY80
C	VAL81
C	TYR86
C	ASN89
C	GLY91
C	HOH317
C	HOH346
C	HOH371

---

site_id	AC5
Number of Residues	9
Details	binding site for residue BTB D 200

Chain	Residue
C	SER67
D	GLY80
D	VAL81
D	VAL82
D	TYR86
D	ASN89
D	GLY91
D	HOH304
D	HOH310

---

site_id	AC6
Number of Residues	13
Details	binding site for residue BTB E 200

Chain	Residue
E	LEU46
E	SER67
E	ALA79
E	GLY80
E	VAL81
E	VAL82
E	TYR86
E	ASN89
E	LEU90
E	GLY91
E	HOH301
E	HOH326
E	HOH331

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