5VIS
1.73 Angstrom Resolution Crystal Structure of Dihydropteroate Synthase (folP-SMZ_B27) from Soil Uncultured Bacterium.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004156 | molecular_function | dihydropteroate synthase activity |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0042558 | biological_process | pteridine-containing compound metabolic process |
| A | 0044237 | biological_process | cellular metabolic process |
| B | 0004156 | molecular_function | dihydropteroate synthase activity |
| B | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| B | 0042558 | biological_process | pteridine-containing compound metabolic process |
| B | 0044237 | biological_process | cellular metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue MLA A 301 |
| Chain | Residue |
| A | LYS225 |
| B | HOH410 |
| B | HOH478 |
| B | HOH501 |
| A | THR226 |
| A | ARG229 |
| A | HOH450 |
| A | HOH609 |
| B | LYS225 |
| B | THR226 |
| B | ARG229 |
| B | TAR303 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 301 |
| Chain | Residue |
| B | VAL147 |
| B | VAL147 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue K B 302 |
| Chain | Residue |
| B | GLU49 |
| B | ASP86 |
| B | HOH447 |
| B | HOH509 |
| B | HOH513 |
| B | HOH579 |
| B | HOH622 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue TAR B 303 |
| Chain | Residue |
| A | LYS225 |
| A | ARG229 |
| A | MLA301 |
| A | HOH609 |
| B | PHE141 |
| B | HIS182 |
| B | SER216 |
| B | ARG229 |
| B | HOH402 |
| B | HOH406 |
| B | HOH410 |
| B | HOH501 |
| B | HOH623 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 304 |
| Chain | Residue |
| B | MET1 |
| B | SER199 |
| B | GLN202 |
| B | LEU242 |
| B | HOH570 |
Functional Information from PROSITE/UniProt
| site_id | PS00792 |
| Number of Residues | 16 |
| Details | DHPS_1 Dihydropteroate synthase signature 1. IvGILNvTpNSFhDgG |
| Chain | Residue | Details |
| A | ILE6-GLY21 |
