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5VHY

GluA2-2xGSG1L bound to ZK

Functional Information from GO Data
ChainGOidnamespacecontents
A0000149molecular_functionSNARE binding
A0001540molecular_functionamyloid-beta binding
A0001919biological_processregulation of receptor recycling
A0004970molecular_functionglutamate-gated receptor activity
A0004971molecular_functionAMPA glutamate receptor activity
A0005216molecular_functionmonoatomic ion channel activity
A0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
A0005234molecular_functionextracellularly glutamate-gated ion channel activity
A0005515molecular_functionprotein binding
A0005783cellular_componentendoplasmic reticulum
A0005886cellular_componentplasma membrane
A0006811biological_processmonoatomic ion transport
A0007268biological_processchemical synaptic transmission
A0008021cellular_componentsynaptic vesicle
A0008092molecular_functioncytoskeletal protein binding
A0008328cellular_componentionotropic glutamate receptor complex
A0009897cellular_componentexternal side of plasma membrane
A0009986cellular_componentcell surface
A0010226biological_processresponse to lithium ion
A0014069cellular_componentpostsynaptic density
A0015276molecular_functionligand-gated monoatomic ion channel activity
A0015277molecular_functionkainate selective glutamate receptor activity
A0016020cellular_componentmembrane
A0019722biological_processcalcium-mediated signaling
A0019865molecular_functionimmunoglobulin binding
A0019901molecular_functionprotein kinase binding
A0021987biological_processcerebral cortex development
A0022849molecular_functionglutamate-gated calcium ion channel activity
A0030165molecular_functionPDZ domain binding
A0030424cellular_componentaxon
A0030425cellular_componentdendrite
A0030426cellular_componentgrowth cone
A0030672cellular_componentsynaptic vesicle membrane
A0031623biological_processreceptor internalization
A0032279cellular_componentasymmetric synapse
A0032281cellular_componentAMPA glutamate receptor complex
A0032590cellular_componentdendrite membrane
A0032839cellular_componentdendrite cytoplasm
A0032991cellular_componentprotein-containing complex
A0034220biological_processmonoatomic ion transmembrane transport
A0035235biological_processionotropic glutamate receptor signaling pathway
A0035249biological_processsynaptic transmission, glutamatergic
A0035254molecular_functionglutamate receptor binding
A0035255molecular_functionionotropic glutamate receptor binding
A0036477cellular_componentsomatodendritic compartment
A0038023molecular_functionsignaling receptor activity
A0042734cellular_componentpresynaptic membrane
A0042802molecular_functionidentical protein binding
A0043005cellular_componentneuron projection
A0043025cellular_componentneuronal cell body
A0043195cellular_componentterminal bouton
A0043197cellular_componentdendritic spine
A0043198cellular_componentdendritic shaft
A0043204cellular_componentperikaryon
A0044326cellular_componentdendritic spine neck
A0044327cellular_componentdendritic spine head
A0044877molecular_functionprotein-containing complex binding
A0045184biological_processestablishment of protein localization
A0045202cellular_componentsynapse
A0045211cellular_componentpostsynaptic membrane
A0048787cellular_componentpresynaptic active zone membrane
A0050804biological_processmodulation of chemical synaptic transmission
A0050806biological_processpositive regulation of synaptic transmission
A0051262biological_processprotein tetramerization
A0051913biological_processregulation of synaptic plasticity by chemical substance
A0051966biological_processregulation of synaptic transmission, glutamatergic
A0060076cellular_componentexcitatory synapse
A0060078biological_processregulation of postsynaptic membrane potential
A0060079biological_processexcitatory postsynaptic potential
A0060291biological_processlong-term synaptic potentiation
A0060992biological_processresponse to fungicide
A0061846cellular_componentdendritic spine cytoplasm
A0071418biological_processcellular response to amine stimulus
A0097060cellular_componentsynaptic membrane
A0097110molecular_functionscaffold protein binding
A0097113biological_processAMPA glutamate receptor clustering
A0098655biological_processmonoatomic cation transmembrane transport
A0098685cellular_componentSchaffer collateral - CA1 synapse
A0098793cellular_componentpresynapse
A0098839cellular_componentpostsynaptic density membrane
A0098978cellular_componentglutamatergic synapse
A0099094molecular_functionligand-gated monoatomic cation channel activity
A0099505biological_processregulation of presynaptic membrane potential
A0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
A0099544cellular_componentperisynaptic space
A0106033cellular_componentspine synapse
A1900452biological_processregulation of long-term synaptic depression
A1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
A1905430biological_processcellular response to glycine
A1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
A1990708biological_processconditioned place preference
A2000463biological_processpositive regulation of excitatory postsynaptic potential
B0000149molecular_functionSNARE binding
B0001540molecular_functionamyloid-beta binding
B0001919biological_processregulation of receptor recycling
B0004970molecular_functionglutamate-gated receptor activity
B0004971molecular_functionAMPA glutamate receptor activity
B0005216molecular_functionmonoatomic ion channel activity
B0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
B0005234molecular_functionextracellularly glutamate-gated ion channel activity
B0005515molecular_functionprotein binding
B0005783cellular_componentendoplasmic reticulum
B0005886cellular_componentplasma membrane
B0006811biological_processmonoatomic ion transport
B0007268biological_processchemical synaptic transmission
B0008021cellular_componentsynaptic vesicle
B0008092molecular_functioncytoskeletal protein binding
B0008328cellular_componentionotropic glutamate receptor complex
B0009897cellular_componentexternal side of plasma membrane
B0009986cellular_componentcell surface
B0010226biological_processresponse to lithium ion
B0014069cellular_componentpostsynaptic density
B0015276molecular_functionligand-gated monoatomic ion channel activity
B0015277molecular_functionkainate selective glutamate receptor activity
B0016020cellular_componentmembrane
B0019722biological_processcalcium-mediated signaling
B0019865molecular_functionimmunoglobulin binding
B0019901molecular_functionprotein kinase binding
B0021987biological_processcerebral cortex development
B0022849molecular_functionglutamate-gated calcium ion channel activity
B0030165molecular_functionPDZ domain binding
B0030424cellular_componentaxon
B0030425cellular_componentdendrite
B0030426cellular_componentgrowth cone
B0030672cellular_componentsynaptic vesicle membrane
B0031623biological_processreceptor internalization
B0032279cellular_componentasymmetric synapse
B0032281cellular_componentAMPA glutamate receptor complex
B0032590cellular_componentdendrite membrane
B0032839cellular_componentdendrite cytoplasm
B0032991cellular_componentprotein-containing complex
B0034220biological_processmonoatomic ion transmembrane transport
B0035235biological_processionotropic glutamate receptor signaling pathway
B0035249biological_processsynaptic transmission, glutamatergic
B0035254molecular_functionglutamate receptor binding
B0035255molecular_functionionotropic glutamate receptor binding
B0036477cellular_componentsomatodendritic compartment
B0038023molecular_functionsignaling receptor activity
B0042734cellular_componentpresynaptic membrane
B0042802molecular_functionidentical protein binding
B0043005cellular_componentneuron projection
B0043025cellular_componentneuronal cell body
B0043195cellular_componentterminal bouton
B0043197cellular_componentdendritic spine
B0043198cellular_componentdendritic shaft
B0043204cellular_componentperikaryon
B0044326cellular_componentdendritic spine neck
B0044327cellular_componentdendritic spine head
B0044877molecular_functionprotein-containing complex binding
B0045184biological_processestablishment of protein localization
B0045202cellular_componentsynapse
B0045211cellular_componentpostsynaptic membrane
B0048787cellular_componentpresynaptic active zone membrane
B0050804biological_processmodulation of chemical synaptic transmission
B0050806biological_processpositive regulation of synaptic transmission
B0051262biological_processprotein tetramerization
B0051913biological_processregulation of synaptic plasticity by chemical substance
B0051966biological_processregulation of synaptic transmission, glutamatergic
B0060076cellular_componentexcitatory synapse
B0060078biological_processregulation of postsynaptic membrane potential
B0060079biological_processexcitatory postsynaptic potential
B0060291biological_processlong-term synaptic potentiation
B0060992biological_processresponse to fungicide
B0061846cellular_componentdendritic spine cytoplasm
B0071418biological_processcellular response to amine stimulus
B0097060cellular_componentsynaptic membrane
B0097110molecular_functionscaffold protein binding
B0097113biological_processAMPA glutamate receptor clustering
B0098655biological_processmonoatomic cation transmembrane transport
B0098685cellular_componentSchaffer collateral - CA1 synapse
B0098793cellular_componentpresynapse
B0098839cellular_componentpostsynaptic density membrane
B0098978cellular_componentglutamatergic synapse
B0099094molecular_functionligand-gated monoatomic cation channel activity
B0099505biological_processregulation of presynaptic membrane potential
B0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
B0099544cellular_componentperisynaptic space
B0106033cellular_componentspine synapse
B1900452biological_processregulation of long-term synaptic depression
B1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
B1905430biological_processcellular response to glycine
B1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
B1990708biological_processconditioned place preference
B2000463biological_processpositive regulation of excitatory postsynaptic potential
C0000149molecular_functionSNARE binding
C0001540molecular_functionamyloid-beta binding
C0001919biological_processregulation of receptor recycling
C0004970molecular_functionglutamate-gated receptor activity
C0004971molecular_functionAMPA glutamate receptor activity
C0005216molecular_functionmonoatomic ion channel activity
C0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
C0005234molecular_functionextracellularly glutamate-gated ion channel activity
C0005515molecular_functionprotein binding
C0005783cellular_componentendoplasmic reticulum
C0005886cellular_componentplasma membrane
C0006811biological_processmonoatomic ion transport
C0007268biological_processchemical synaptic transmission
C0008021cellular_componentsynaptic vesicle
C0008092molecular_functioncytoskeletal protein binding
C0008328cellular_componentionotropic glutamate receptor complex
C0009897cellular_componentexternal side of plasma membrane
C0009986cellular_componentcell surface
C0010226biological_processresponse to lithium ion
C0014069cellular_componentpostsynaptic density
C0015276molecular_functionligand-gated monoatomic ion channel activity
C0015277molecular_functionkainate selective glutamate receptor activity
C0016020cellular_componentmembrane
C0019722biological_processcalcium-mediated signaling
C0019865molecular_functionimmunoglobulin binding
C0019901molecular_functionprotein kinase binding
C0021987biological_processcerebral cortex development
C0022849molecular_functionglutamate-gated calcium ion channel activity
C0030165molecular_functionPDZ domain binding
C0030424cellular_componentaxon
C0030425cellular_componentdendrite
C0030426cellular_componentgrowth cone
C0030672cellular_componentsynaptic vesicle membrane
C0031623biological_processreceptor internalization
C0032279cellular_componentasymmetric synapse
C0032281cellular_componentAMPA glutamate receptor complex
C0032590cellular_componentdendrite membrane
C0032839cellular_componentdendrite cytoplasm
C0032991cellular_componentprotein-containing complex
C0034220biological_processmonoatomic ion transmembrane transport
C0035235biological_processionotropic glutamate receptor signaling pathway
C0035249biological_processsynaptic transmission, glutamatergic
C0035254molecular_functionglutamate receptor binding
C0035255molecular_functionionotropic glutamate receptor binding
C0036477cellular_componentsomatodendritic compartment
C0038023molecular_functionsignaling receptor activity
C0042734cellular_componentpresynaptic membrane
C0042802molecular_functionidentical protein binding
C0043005cellular_componentneuron projection
C0043025cellular_componentneuronal cell body
C0043195cellular_componentterminal bouton
C0043197cellular_componentdendritic spine
C0043198cellular_componentdendritic shaft
C0043204cellular_componentperikaryon
C0044326cellular_componentdendritic spine neck
C0044327cellular_componentdendritic spine head
C0044877molecular_functionprotein-containing complex binding
C0045184biological_processestablishment of protein localization
C0045202cellular_componentsynapse
C0045211cellular_componentpostsynaptic membrane
C0048787cellular_componentpresynaptic active zone membrane
C0050804biological_processmodulation of chemical synaptic transmission
C0050806biological_processpositive regulation of synaptic transmission
C0051262biological_processprotein tetramerization
C0051913biological_processregulation of synaptic plasticity by chemical substance
C0051966biological_processregulation of synaptic transmission, glutamatergic
C0060076cellular_componentexcitatory synapse
C0060078biological_processregulation of postsynaptic membrane potential
C0060079biological_processexcitatory postsynaptic potential
C0060291biological_processlong-term synaptic potentiation
C0060992biological_processresponse to fungicide
C0061846cellular_componentdendritic spine cytoplasm
C0071418biological_processcellular response to amine stimulus
C0097060cellular_componentsynaptic membrane
C0097110molecular_functionscaffold protein binding
C0097113biological_processAMPA glutamate receptor clustering
C0098655biological_processmonoatomic cation transmembrane transport
C0098685cellular_componentSchaffer collateral - CA1 synapse
C0098793cellular_componentpresynapse
C0098839cellular_componentpostsynaptic density membrane
C0098978cellular_componentglutamatergic synapse
C0099094molecular_functionligand-gated monoatomic cation channel activity
C0099505biological_processregulation of presynaptic membrane potential
C0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
C0099544cellular_componentperisynaptic space
C0106033cellular_componentspine synapse
C1900452biological_processregulation of long-term synaptic depression
C1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
C1905430biological_processcellular response to glycine
C1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
C1990708biological_processconditioned place preference
C2000463biological_processpositive regulation of excitatory postsynaptic potential
D0000149molecular_functionSNARE binding
D0001540molecular_functionamyloid-beta binding
D0001919biological_processregulation of receptor recycling
D0004970molecular_functionglutamate-gated receptor activity
D0004971molecular_functionAMPA glutamate receptor activity
D0005216molecular_functionmonoatomic ion channel activity
D0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
D0005234molecular_functionextracellularly glutamate-gated ion channel activity
D0005515molecular_functionprotein binding
D0005783cellular_componentendoplasmic reticulum
D0005886cellular_componentplasma membrane
D0006811biological_processmonoatomic ion transport
D0007268biological_processchemical synaptic transmission
D0008021cellular_componentsynaptic vesicle
D0008092molecular_functioncytoskeletal protein binding
D0008328cellular_componentionotropic glutamate receptor complex
D0009897cellular_componentexternal side of plasma membrane
D0009986cellular_componentcell surface
D0010226biological_processresponse to lithium ion
D0014069cellular_componentpostsynaptic density
D0015276molecular_functionligand-gated monoatomic ion channel activity
D0015277molecular_functionkainate selective glutamate receptor activity
D0016020cellular_componentmembrane
D0019722biological_processcalcium-mediated signaling
D0019865molecular_functionimmunoglobulin binding
D0019901molecular_functionprotein kinase binding
D0021987biological_processcerebral cortex development
D0022849molecular_functionglutamate-gated calcium ion channel activity
D0030165molecular_functionPDZ domain binding
D0030424cellular_componentaxon
D0030425cellular_componentdendrite
D0030426cellular_componentgrowth cone
D0030672cellular_componentsynaptic vesicle membrane
D0031623biological_processreceptor internalization
D0032279cellular_componentasymmetric synapse
D0032281cellular_componentAMPA glutamate receptor complex
D0032590cellular_componentdendrite membrane
D0032839cellular_componentdendrite cytoplasm
D0032991cellular_componentprotein-containing complex
D0034220biological_processmonoatomic ion transmembrane transport
D0035235biological_processionotropic glutamate receptor signaling pathway
D0035249biological_processsynaptic transmission, glutamatergic
D0035254molecular_functionglutamate receptor binding
D0035255molecular_functionionotropic glutamate receptor binding
D0036477cellular_componentsomatodendritic compartment
D0038023molecular_functionsignaling receptor activity
D0042734cellular_componentpresynaptic membrane
D0042802molecular_functionidentical protein binding
D0043005cellular_componentneuron projection
D0043025cellular_componentneuronal cell body
D0043195cellular_componentterminal bouton
D0043197cellular_componentdendritic spine
D0043198cellular_componentdendritic shaft
D0043204cellular_componentperikaryon
D0044326cellular_componentdendritic spine neck
D0044327cellular_componentdendritic spine head
D0044877molecular_functionprotein-containing complex binding
D0045184biological_processestablishment of protein localization
D0045202cellular_componentsynapse
D0045211cellular_componentpostsynaptic membrane
D0048787cellular_componentpresynaptic active zone membrane
D0050804biological_processmodulation of chemical synaptic transmission
D0050806biological_processpositive regulation of synaptic transmission
D0051262biological_processprotein tetramerization
D0051913biological_processregulation of synaptic plasticity by chemical substance
D0051966biological_processregulation of synaptic transmission, glutamatergic
D0060076cellular_componentexcitatory synapse
D0060078biological_processregulation of postsynaptic membrane potential
D0060079biological_processexcitatory postsynaptic potential
D0060291biological_processlong-term synaptic potentiation
D0060992biological_processresponse to fungicide
D0061846cellular_componentdendritic spine cytoplasm
D0071418biological_processcellular response to amine stimulus
D0097060cellular_componentsynaptic membrane
D0097110molecular_functionscaffold protein binding
D0097113biological_processAMPA glutamate receptor clustering
D0098655biological_processmonoatomic cation transmembrane transport
D0098685cellular_componentSchaffer collateral - CA1 synapse
D0098793cellular_componentpresynapse
D0098839cellular_componentpostsynaptic density membrane
D0098978cellular_componentglutamatergic synapse
D0099094molecular_functionligand-gated monoatomic cation channel activity
D0099505biological_processregulation of presynaptic membrane potential
D0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
D0099544cellular_componentperisynaptic space
D0106033cellular_componentspine synapse
D1900452biological_processregulation of long-term synaptic depression
D1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
D1905430biological_processcellular response to glycine
D1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
D1990708biological_processconditioned place preference
D2000463biological_processpositive regulation of excitatory postsynaptic potential
E0000149molecular_functionSNARE binding
E0001540molecular_functionamyloid-beta binding
E0001919biological_processregulation of receptor recycling
E0004970molecular_functionglutamate-gated receptor activity
E0004971molecular_functionAMPA glutamate receptor activity
E0005216molecular_functionmonoatomic ion channel activity
E0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
E0005234molecular_functionextracellularly glutamate-gated ion channel activity
E0005515molecular_functionprotein binding
E0005783cellular_componentendoplasmic reticulum
E0005886cellular_componentplasma membrane
E0006811biological_processmonoatomic ion transport
E0007268biological_processchemical synaptic transmission
E0008021cellular_componentsynaptic vesicle
E0008092molecular_functioncytoskeletal protein binding
E0008328cellular_componentionotropic glutamate receptor complex
E0009897cellular_componentexternal side of plasma membrane
E0009986cellular_componentcell surface
E0010226biological_processresponse to lithium ion
E0014069cellular_componentpostsynaptic density
E0015276molecular_functionligand-gated monoatomic ion channel activity
E0015277molecular_functionkainate selective glutamate receptor activity
E0016020cellular_componentmembrane
E0019722biological_processcalcium-mediated signaling
E0019865molecular_functionimmunoglobulin binding
E0019901molecular_functionprotein kinase binding
E0021987biological_processcerebral cortex development
E0022849molecular_functionglutamate-gated calcium ion channel activity
E0030165molecular_functionPDZ domain binding
E0030424cellular_componentaxon
E0030425cellular_componentdendrite
E0030426cellular_componentgrowth cone
E0030672cellular_componentsynaptic vesicle membrane
E0031623biological_processreceptor internalization
E0032279cellular_componentasymmetric synapse
E0032281cellular_componentAMPA glutamate receptor complex
E0032590cellular_componentdendrite membrane
E0032839cellular_componentdendrite cytoplasm
E0032991cellular_componentprotein-containing complex
E0034220biological_processmonoatomic ion transmembrane transport
E0035235biological_processionotropic glutamate receptor signaling pathway
E0035249biological_processsynaptic transmission, glutamatergic
E0035254molecular_functionglutamate receptor binding
E0035255molecular_functionionotropic glutamate receptor binding
E0036477cellular_componentsomatodendritic compartment
E0038023molecular_functionsignaling receptor activity
E0042734cellular_componentpresynaptic membrane
E0042802molecular_functionidentical protein binding
E0043005cellular_componentneuron projection
E0043025cellular_componentneuronal cell body
E0043195cellular_componentterminal bouton
E0043197cellular_componentdendritic spine
E0043198cellular_componentdendritic shaft
E0043204cellular_componentperikaryon
E0044326cellular_componentdendritic spine neck
E0044327cellular_componentdendritic spine head
E0044877molecular_functionprotein-containing complex binding
E0045184biological_processestablishment of protein localization
E0045202cellular_componentsynapse
E0045211cellular_componentpostsynaptic membrane
E0048787cellular_componentpresynaptic active zone membrane
E0050804biological_processmodulation of chemical synaptic transmission
E0050806biological_processpositive regulation of synaptic transmission
E0051262biological_processprotein tetramerization
E0051913biological_processregulation of synaptic plasticity by chemical substance
E0051966biological_processregulation of synaptic transmission, glutamatergic
E0060076cellular_componentexcitatory synapse
E0060078biological_processregulation of postsynaptic membrane potential
E0060079biological_processexcitatory postsynaptic potential
E0060291biological_processlong-term synaptic potentiation
E0060992biological_processresponse to fungicide
E0061846cellular_componentdendritic spine cytoplasm
E0071418biological_processcellular response to amine stimulus
E0097060cellular_componentsynaptic membrane
E0097110molecular_functionscaffold protein binding
E0097113biological_processAMPA glutamate receptor clustering
E0098655biological_processmonoatomic cation transmembrane transport
E0098685cellular_componentSchaffer collateral - CA1 synapse
E0098793cellular_componentpresynapse
E0098839cellular_componentpostsynaptic density membrane
E0098978cellular_componentglutamatergic synapse
E0099094molecular_functionligand-gated monoatomic cation channel activity
E0099505biological_processregulation of presynaptic membrane potential
E0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
E0099544cellular_componentperisynaptic space
E0106033cellular_componentspine synapse
E1900452biological_processregulation of long-term synaptic depression
E1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
E1905430biological_processcellular response to glycine
E1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
E1990708biological_processconditioned place preference
E2000463biological_processpositive regulation of excitatory postsynaptic potential
F0000149molecular_functionSNARE binding
F0001540molecular_functionamyloid-beta binding
F0001919biological_processregulation of receptor recycling
F0004970molecular_functionglutamate-gated receptor activity
F0004971molecular_functionAMPA glutamate receptor activity
F0005216molecular_functionmonoatomic ion channel activity
F0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
F0005234molecular_functionextracellularly glutamate-gated ion channel activity
F0005515molecular_functionprotein binding
F0005783cellular_componentendoplasmic reticulum
F0005886cellular_componentplasma membrane
F0006811biological_processmonoatomic ion transport
F0007268biological_processchemical synaptic transmission
F0008021cellular_componentsynaptic vesicle
F0008092molecular_functioncytoskeletal protein binding
F0008328cellular_componentionotropic glutamate receptor complex
F0009897cellular_componentexternal side of plasma membrane
F0009986cellular_componentcell surface
F0010226biological_processresponse to lithium ion
F0014069cellular_componentpostsynaptic density
F0015276molecular_functionligand-gated monoatomic ion channel activity
F0015277molecular_functionkainate selective glutamate receptor activity
F0016020cellular_componentmembrane
F0019722biological_processcalcium-mediated signaling
F0019865molecular_functionimmunoglobulin binding
F0019901molecular_functionprotein kinase binding
F0021987biological_processcerebral cortex development
F0022849molecular_functionglutamate-gated calcium ion channel activity
F0030165molecular_functionPDZ domain binding
F0030424cellular_componentaxon
F0030425cellular_componentdendrite
F0030426cellular_componentgrowth cone
F0030672cellular_componentsynaptic vesicle membrane
F0031623biological_processreceptor internalization
F0032279cellular_componentasymmetric synapse
F0032281cellular_componentAMPA glutamate receptor complex
F0032590cellular_componentdendrite membrane
F0032839cellular_componentdendrite cytoplasm
F0032991cellular_componentprotein-containing complex
F0034220biological_processmonoatomic ion transmembrane transport
F0035235biological_processionotropic glutamate receptor signaling pathway
F0035249biological_processsynaptic transmission, glutamatergic
F0035254molecular_functionglutamate receptor binding
F0035255molecular_functionionotropic glutamate receptor binding
F0036477cellular_componentsomatodendritic compartment
F0038023molecular_functionsignaling receptor activity
F0042734cellular_componentpresynaptic membrane
F0042802molecular_functionidentical protein binding
F0043005cellular_componentneuron projection
F0043025cellular_componentneuronal cell body
F0043195cellular_componentterminal bouton
F0043197cellular_componentdendritic spine
F0043198cellular_componentdendritic shaft
F0043204cellular_componentperikaryon
F0044326cellular_componentdendritic spine neck
F0044327cellular_componentdendritic spine head
F0044877molecular_functionprotein-containing complex binding
F0045184biological_processestablishment of protein localization
F0045202cellular_componentsynapse
F0045211cellular_componentpostsynaptic membrane
F0048787cellular_componentpresynaptic active zone membrane
F0050804biological_processmodulation of chemical synaptic transmission
F0050806biological_processpositive regulation of synaptic transmission
F0051262biological_processprotein tetramerization
F0051913biological_processregulation of synaptic plasticity by chemical substance
F0051966biological_processregulation of synaptic transmission, glutamatergic
F0060076cellular_componentexcitatory synapse
F0060078biological_processregulation of postsynaptic membrane potential
F0060079biological_processexcitatory postsynaptic potential
F0060291biological_processlong-term synaptic potentiation
F0060992biological_processresponse to fungicide
F0061846cellular_componentdendritic spine cytoplasm
F0071418biological_processcellular response to amine stimulus
F0097060cellular_componentsynaptic membrane
F0097110molecular_functionscaffold protein binding
F0097113biological_processAMPA glutamate receptor clustering
F0098655biological_processmonoatomic cation transmembrane transport
F0098685cellular_componentSchaffer collateral - CA1 synapse
F0098793cellular_componentpresynapse
F0098839cellular_componentpostsynaptic density membrane
F0098978cellular_componentglutamatergic synapse
F0099094molecular_functionligand-gated monoatomic cation channel activity
F0099505biological_processregulation of presynaptic membrane potential
F0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
F0099544cellular_componentperisynaptic space
F0106033cellular_componentspine synapse
F1900452biological_processregulation of long-term synaptic depression
F1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
F1905430biological_processcellular response to glycine
F1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
F1990708biological_processconditioned place preference
F2000463biological_processpositive regulation of excitatory postsynaptic potential
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues160
DetailsTransmembrane: {"description":"Helical"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues8
DetailsIntramembrane: {}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues20
DetailsTopological domain: {"description":"Cytoplasmic"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues696
DetailsTopological domain: {"description":"Extracellular"}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues80
DetailsTransmembrane: {"description":"Helical; Name=M4"}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues24
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"11086992","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16483599","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FTJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CMO","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues12
DetailsSite: {"description":"Interaction with the cone snail toxin Con-ikot-ikot","evidences":[{"source":"PubMed","id":"25103405","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues4
DetailsSite: {"description":"Crucial to convey clamshell closure to channel opening","evidences":[{"source":"PubMed","id":"25103405","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI9
Number of Residues4
DetailsModified residue: {"description":"Phosphoserine; by PKC","evidences":[{"source":"PubMed","id":"8848293","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI10
Number of Residues4
DetailsModified residue: {"description":"Phosphoserine; by PKG","evidences":[{"source":"PubMed","id":"8848293","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI11
Number of Residues8
DetailsLipidation: {"description":"S-palmitoyl cysteine","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI12
Number of Residues4
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"21317873","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI13
Number of Residues4
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19946266","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21317873","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25103405","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI14
Number of Residues8
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI15
Number of Residues160
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI16
Number of Residues44
DetailsTopological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246704

PDB entries from 2025-12-24

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