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5VHX

GluA2-1xGSG1L bound to ZK

Functional Information from GO Data
ChainGOidnamespacecontents
A0000149molecular_functionSNARE binding
A0001540molecular_functionamyloid-beta binding
A0001919biological_processregulation of receptor recycling
A0004970molecular_functionglutamate-gated receptor activity
A0004971molecular_functionAMPA glutamate receptor activity
A0005216molecular_functionmonoatomic ion channel activity
A0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
A0005234molecular_functionextracellularly glutamate-gated ion channel activity
A0005515molecular_functionprotein binding
A0005783cellular_componentendoplasmic reticulum
A0005886cellular_componentplasma membrane
A0006811biological_processmonoatomic ion transport
A0007268biological_processchemical synaptic transmission
A0008021cellular_componentsynaptic vesicle
A0008092molecular_functioncytoskeletal protein binding
A0008328cellular_componentionotropic glutamate receptor complex
A0009986cellular_componentcell surface
A0010226biological_processresponse to lithium ion
A0014069cellular_componentpostsynaptic density
A0015276molecular_functionligand-gated monoatomic ion channel activity
A0015277molecular_functionkainate selective glutamate receptor activity
A0016020cellular_componentmembrane
A0019722biological_processcalcium-mediated signaling
A0019865molecular_functionimmunoglobulin binding
A0019901molecular_functionprotein kinase binding
A0021987biological_processcerebral cortex development
A0022849molecular_functionglutamate-gated calcium ion channel activity
A0022890molecular_functioninorganic cation transmembrane transporter activity
A0030165molecular_functionPDZ domain binding
A0030424cellular_componentaxon
A0030425cellular_componentdendrite
A0030426cellular_componentgrowth cone
A0030672cellular_componentsynaptic vesicle membrane
A0031623biological_processreceptor internalization
A0032279cellular_componentasymmetric synapse
A0032281cellular_componentAMPA glutamate receptor complex
A0032590cellular_componentdendrite membrane
A0032839cellular_componentdendrite cytoplasm
A0032991cellular_componentprotein-containing complex
A0034220biological_processmonoatomic ion transmembrane transport
A0035235biological_processionotropic glutamate receptor signaling pathway
A0035249biological_processsynaptic transmission, glutamatergic
A0035254molecular_functionglutamate receptor binding
A0035255molecular_functionionotropic glutamate receptor binding
A0036477cellular_componentsomatodendritic compartment
A0038023molecular_functionsignaling receptor activity
A0042734cellular_componentpresynaptic membrane
A0042802molecular_functionidentical protein binding
A0043005cellular_componentneuron projection
A0043025cellular_componentneuronal cell body
A0043195cellular_componentterminal bouton
A0043197cellular_componentdendritic spine
A0043198cellular_componentdendritic shaft
A0043204cellular_componentperikaryon
A0043226cellular_componentorganelle
A0044326cellular_componentdendritic spine neck
A0044327cellular_componentdendritic spine head
A0044877molecular_functionprotein-containing complex binding
A0045184biological_processestablishment of protein localization
A0045202cellular_componentsynapse
A0045211cellular_componentpostsynaptic membrane
A0048787cellular_componentpresynaptic active zone membrane
A0050804biological_processmodulation of chemical synaptic transmission
A0050806biological_processpositive regulation of synaptic transmission
A0051262biological_processprotein tetramerization
A0051966biological_processregulation of synaptic transmission, glutamatergic
A0060078biological_processregulation of postsynaptic membrane potential
A0060079biological_processexcitatory postsynaptic potential
A0060992biological_processresponse to fungicide
A0097060cellular_componentsynaptic membrane
A0097110molecular_functionscaffold protein binding
A0098655biological_processmonoatomic cation transmembrane transport
A0098685cellular_componentSchaffer collateral - CA1 synapse
A0098793cellular_componentpresynapse
A0098839cellular_componentpostsynaptic density membrane
A0098978cellular_componentglutamatergic synapse
A0099094molecular_functionligand-gated monoatomic cation channel activity
A0099505biological_processregulation of presynaptic membrane potential
A0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
A0099544cellular_componentperisynaptic space
A0106033cellular_componentspine synapse
A1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
A1905430biological_processcellular response to glycine
A1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
B0000149molecular_functionSNARE binding
B0001540molecular_functionamyloid-beta binding
B0001919biological_processregulation of receptor recycling
B0004970molecular_functionglutamate-gated receptor activity
B0004971molecular_functionAMPA glutamate receptor activity
B0005216molecular_functionmonoatomic ion channel activity
B0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
B0005234molecular_functionextracellularly glutamate-gated ion channel activity
B0005515molecular_functionprotein binding
B0005783cellular_componentendoplasmic reticulum
B0005886cellular_componentplasma membrane
B0006811biological_processmonoatomic ion transport
B0007268biological_processchemical synaptic transmission
B0008021cellular_componentsynaptic vesicle
B0008092molecular_functioncytoskeletal protein binding
B0008328cellular_componentionotropic glutamate receptor complex
B0009986cellular_componentcell surface
B0010226biological_processresponse to lithium ion
B0014069cellular_componentpostsynaptic density
B0015276molecular_functionligand-gated monoatomic ion channel activity
B0015277molecular_functionkainate selective glutamate receptor activity
B0016020cellular_componentmembrane
B0019722biological_processcalcium-mediated signaling
B0019865molecular_functionimmunoglobulin binding
B0019901molecular_functionprotein kinase binding
B0021987biological_processcerebral cortex development
B0022849molecular_functionglutamate-gated calcium ion channel activity
B0022890molecular_functioninorganic cation transmembrane transporter activity
B0030165molecular_functionPDZ domain binding
B0030424cellular_componentaxon
B0030425cellular_componentdendrite
B0030426cellular_componentgrowth cone
B0030672cellular_componentsynaptic vesicle membrane
B0031623biological_processreceptor internalization
B0032279cellular_componentasymmetric synapse
B0032281cellular_componentAMPA glutamate receptor complex
B0032590cellular_componentdendrite membrane
B0032839cellular_componentdendrite cytoplasm
B0032991cellular_componentprotein-containing complex
B0034220biological_processmonoatomic ion transmembrane transport
B0035235biological_processionotropic glutamate receptor signaling pathway
B0035249biological_processsynaptic transmission, glutamatergic
B0035254molecular_functionglutamate receptor binding
B0035255molecular_functionionotropic glutamate receptor binding
B0036477cellular_componentsomatodendritic compartment
B0038023molecular_functionsignaling receptor activity
B0042734cellular_componentpresynaptic membrane
B0042802molecular_functionidentical protein binding
B0043005cellular_componentneuron projection
B0043025cellular_componentneuronal cell body
B0043195cellular_componentterminal bouton
B0043197cellular_componentdendritic spine
B0043198cellular_componentdendritic shaft
B0043204cellular_componentperikaryon
B0043226cellular_componentorganelle
B0044326cellular_componentdendritic spine neck
B0044327cellular_componentdendritic spine head
B0044877molecular_functionprotein-containing complex binding
B0045184biological_processestablishment of protein localization
B0045202cellular_componentsynapse
B0045211cellular_componentpostsynaptic membrane
B0048787cellular_componentpresynaptic active zone membrane
B0050804biological_processmodulation of chemical synaptic transmission
B0050806biological_processpositive regulation of synaptic transmission
B0051262biological_processprotein tetramerization
B0051966biological_processregulation of synaptic transmission, glutamatergic
B0060078biological_processregulation of postsynaptic membrane potential
B0060079biological_processexcitatory postsynaptic potential
B0060992biological_processresponse to fungicide
B0097060cellular_componentsynaptic membrane
B0097110molecular_functionscaffold protein binding
B0098655biological_processmonoatomic cation transmembrane transport
B0098685cellular_componentSchaffer collateral - CA1 synapse
B0098793cellular_componentpresynapse
B0098839cellular_componentpostsynaptic density membrane
B0098978cellular_componentglutamatergic synapse
B0099094molecular_functionligand-gated monoatomic cation channel activity
B0099505biological_processregulation of presynaptic membrane potential
B0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
B0099544cellular_componentperisynaptic space
B0106033cellular_componentspine synapse
B1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
B1905430biological_processcellular response to glycine
B1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
C0000149molecular_functionSNARE binding
C0001540molecular_functionamyloid-beta binding
C0001919biological_processregulation of receptor recycling
C0004970molecular_functionglutamate-gated receptor activity
C0004971molecular_functionAMPA glutamate receptor activity
C0005216molecular_functionmonoatomic ion channel activity
C0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
C0005234molecular_functionextracellularly glutamate-gated ion channel activity
C0005515molecular_functionprotein binding
C0005783cellular_componentendoplasmic reticulum
C0005886cellular_componentplasma membrane
C0006811biological_processmonoatomic ion transport
C0007268biological_processchemical synaptic transmission
C0008021cellular_componentsynaptic vesicle
C0008092molecular_functioncytoskeletal protein binding
C0008328cellular_componentionotropic glutamate receptor complex
C0009986cellular_componentcell surface
C0010226biological_processresponse to lithium ion
C0014069cellular_componentpostsynaptic density
C0015276molecular_functionligand-gated monoatomic ion channel activity
C0015277molecular_functionkainate selective glutamate receptor activity
C0016020cellular_componentmembrane
C0019722biological_processcalcium-mediated signaling
C0019865molecular_functionimmunoglobulin binding
C0019901molecular_functionprotein kinase binding
C0021987biological_processcerebral cortex development
C0022849molecular_functionglutamate-gated calcium ion channel activity
C0022890molecular_functioninorganic cation transmembrane transporter activity
C0030165molecular_functionPDZ domain binding
C0030424cellular_componentaxon
C0030425cellular_componentdendrite
C0030426cellular_componentgrowth cone
C0030672cellular_componentsynaptic vesicle membrane
C0031623biological_processreceptor internalization
C0032279cellular_componentasymmetric synapse
C0032281cellular_componentAMPA glutamate receptor complex
C0032590cellular_componentdendrite membrane
C0032839cellular_componentdendrite cytoplasm
C0032991cellular_componentprotein-containing complex
C0034220biological_processmonoatomic ion transmembrane transport
C0035235biological_processionotropic glutamate receptor signaling pathway
C0035249biological_processsynaptic transmission, glutamatergic
C0035254molecular_functionglutamate receptor binding
C0035255molecular_functionionotropic glutamate receptor binding
C0036477cellular_componentsomatodendritic compartment
C0038023molecular_functionsignaling receptor activity
C0042734cellular_componentpresynaptic membrane
C0042802molecular_functionidentical protein binding
C0043005cellular_componentneuron projection
C0043025cellular_componentneuronal cell body
C0043195cellular_componentterminal bouton
C0043197cellular_componentdendritic spine
C0043198cellular_componentdendritic shaft
C0043204cellular_componentperikaryon
C0043226cellular_componentorganelle
C0044326cellular_componentdendritic spine neck
C0044327cellular_componentdendritic spine head
C0044877molecular_functionprotein-containing complex binding
C0045184biological_processestablishment of protein localization
C0045202cellular_componentsynapse
C0045211cellular_componentpostsynaptic membrane
C0048787cellular_componentpresynaptic active zone membrane
C0050804biological_processmodulation of chemical synaptic transmission
C0050806biological_processpositive regulation of synaptic transmission
C0051262biological_processprotein tetramerization
C0051966biological_processregulation of synaptic transmission, glutamatergic
C0060078biological_processregulation of postsynaptic membrane potential
C0060079biological_processexcitatory postsynaptic potential
C0060992biological_processresponse to fungicide
C0097060cellular_componentsynaptic membrane
C0097110molecular_functionscaffold protein binding
C0098655biological_processmonoatomic cation transmembrane transport
C0098685cellular_componentSchaffer collateral - CA1 synapse
C0098793cellular_componentpresynapse
C0098839cellular_componentpostsynaptic density membrane
C0098978cellular_componentglutamatergic synapse
C0099094molecular_functionligand-gated monoatomic cation channel activity
C0099505biological_processregulation of presynaptic membrane potential
C0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
C0099544cellular_componentperisynaptic space
C0106033cellular_componentspine synapse
C1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
C1905430biological_processcellular response to glycine
C1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
D0000149molecular_functionSNARE binding
D0001540molecular_functionamyloid-beta binding
D0001919biological_processregulation of receptor recycling
D0004970molecular_functionglutamate-gated receptor activity
D0004971molecular_functionAMPA glutamate receptor activity
D0005216molecular_functionmonoatomic ion channel activity
D0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
D0005234molecular_functionextracellularly glutamate-gated ion channel activity
D0005515molecular_functionprotein binding
D0005783cellular_componentendoplasmic reticulum
D0005886cellular_componentplasma membrane
D0006811biological_processmonoatomic ion transport
D0007268biological_processchemical synaptic transmission
D0008021cellular_componentsynaptic vesicle
D0008092molecular_functioncytoskeletal protein binding
D0008328cellular_componentionotropic glutamate receptor complex
D0009986cellular_componentcell surface
D0010226biological_processresponse to lithium ion
D0014069cellular_componentpostsynaptic density
D0015276molecular_functionligand-gated monoatomic ion channel activity
D0015277molecular_functionkainate selective glutamate receptor activity
D0016020cellular_componentmembrane
D0019722biological_processcalcium-mediated signaling
D0019865molecular_functionimmunoglobulin binding
D0019901molecular_functionprotein kinase binding
D0021987biological_processcerebral cortex development
D0022849molecular_functionglutamate-gated calcium ion channel activity
D0022890molecular_functioninorganic cation transmembrane transporter activity
D0030165molecular_functionPDZ domain binding
D0030424cellular_componentaxon
D0030425cellular_componentdendrite
D0030426cellular_componentgrowth cone
D0030672cellular_componentsynaptic vesicle membrane
D0031623biological_processreceptor internalization
D0032279cellular_componentasymmetric synapse
D0032281cellular_componentAMPA glutamate receptor complex
D0032590cellular_componentdendrite membrane
D0032839cellular_componentdendrite cytoplasm
D0032991cellular_componentprotein-containing complex
D0034220biological_processmonoatomic ion transmembrane transport
D0035235biological_processionotropic glutamate receptor signaling pathway
D0035249biological_processsynaptic transmission, glutamatergic
D0035254molecular_functionglutamate receptor binding
D0035255molecular_functionionotropic glutamate receptor binding
D0036477cellular_componentsomatodendritic compartment
D0038023molecular_functionsignaling receptor activity
D0042734cellular_componentpresynaptic membrane
D0042802molecular_functionidentical protein binding
D0043005cellular_componentneuron projection
D0043025cellular_componentneuronal cell body
D0043195cellular_componentterminal bouton
D0043197cellular_componentdendritic spine
D0043198cellular_componentdendritic shaft
D0043204cellular_componentperikaryon
D0043226cellular_componentorganelle
D0044326cellular_componentdendritic spine neck
D0044327cellular_componentdendritic spine head
D0044877molecular_functionprotein-containing complex binding
D0045184biological_processestablishment of protein localization
D0045202cellular_componentsynapse
D0045211cellular_componentpostsynaptic membrane
D0048787cellular_componentpresynaptic active zone membrane
D0050804biological_processmodulation of chemical synaptic transmission
D0050806biological_processpositive regulation of synaptic transmission
D0051262biological_processprotein tetramerization
D0051966biological_processregulation of synaptic transmission, glutamatergic
D0060078biological_processregulation of postsynaptic membrane potential
D0060079biological_processexcitatory postsynaptic potential
D0060992biological_processresponse to fungicide
D0097060cellular_componentsynaptic membrane
D0097110molecular_functionscaffold protein binding
D0098655biological_processmonoatomic cation transmembrane transport
D0098685cellular_componentSchaffer collateral - CA1 synapse
D0098793cellular_componentpresynapse
D0098839cellular_componentpostsynaptic density membrane
D0098978cellular_componentglutamatergic synapse
D0099094molecular_functionligand-gated monoatomic cation channel activity
D0099505biological_processregulation of presynaptic membrane potential
D0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
D0099544cellular_componentperisynaptic space
D0106033cellular_componentspine synapse
D1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
D1905430biological_processcellular response to glycine
D1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
E0000149molecular_functionSNARE binding
E0001540molecular_functionamyloid-beta binding
E0001919biological_processregulation of receptor recycling
E0004970molecular_functionglutamate-gated receptor activity
E0004971molecular_functionAMPA glutamate receptor activity
E0005216molecular_functionmonoatomic ion channel activity
E0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
E0005234molecular_functionextracellularly glutamate-gated ion channel activity
E0005515molecular_functionprotein binding
E0005783cellular_componentendoplasmic reticulum
E0005886cellular_componentplasma membrane
E0006811biological_processmonoatomic ion transport
E0007268biological_processchemical synaptic transmission
E0008021cellular_componentsynaptic vesicle
E0008092molecular_functioncytoskeletal protein binding
E0008328cellular_componentionotropic glutamate receptor complex
E0009986cellular_componentcell surface
E0010226biological_processresponse to lithium ion
E0014069cellular_componentpostsynaptic density
E0015276molecular_functionligand-gated monoatomic ion channel activity
E0015277molecular_functionkainate selective glutamate receptor activity
E0016020cellular_componentmembrane
E0019722biological_processcalcium-mediated signaling
E0019865molecular_functionimmunoglobulin binding
E0019901molecular_functionprotein kinase binding
E0021987biological_processcerebral cortex development
E0022849molecular_functionglutamate-gated calcium ion channel activity
E0022890molecular_functioninorganic cation transmembrane transporter activity
E0030165molecular_functionPDZ domain binding
E0030424cellular_componentaxon
E0030425cellular_componentdendrite
E0030426cellular_componentgrowth cone
E0030672cellular_componentsynaptic vesicle membrane
E0031623biological_processreceptor internalization
E0032279cellular_componentasymmetric synapse
E0032281cellular_componentAMPA glutamate receptor complex
E0032590cellular_componentdendrite membrane
E0032839cellular_componentdendrite cytoplasm
E0032991cellular_componentprotein-containing complex
E0034220biological_processmonoatomic ion transmembrane transport
E0035235biological_processionotropic glutamate receptor signaling pathway
E0035249biological_processsynaptic transmission, glutamatergic
E0035254molecular_functionglutamate receptor binding
E0035255molecular_functionionotropic glutamate receptor binding
E0036477cellular_componentsomatodendritic compartment
E0038023molecular_functionsignaling receptor activity
E0042734cellular_componentpresynaptic membrane
E0042802molecular_functionidentical protein binding
E0043005cellular_componentneuron projection
E0043025cellular_componentneuronal cell body
E0043195cellular_componentterminal bouton
E0043197cellular_componentdendritic spine
E0043198cellular_componentdendritic shaft
E0043204cellular_componentperikaryon
E0043226cellular_componentorganelle
E0044326cellular_componentdendritic spine neck
E0044327cellular_componentdendritic spine head
E0044877molecular_functionprotein-containing complex binding
E0045184biological_processestablishment of protein localization
E0045202cellular_componentsynapse
E0045211cellular_componentpostsynaptic membrane
E0048787cellular_componentpresynaptic active zone membrane
E0050804biological_processmodulation of chemical synaptic transmission
E0050806biological_processpositive regulation of synaptic transmission
E0051262biological_processprotein tetramerization
E0051966biological_processregulation of synaptic transmission, glutamatergic
E0060078biological_processregulation of postsynaptic membrane potential
E0060079biological_processexcitatory postsynaptic potential
E0060992biological_processresponse to fungicide
E0097060cellular_componentsynaptic membrane
E0097110molecular_functionscaffold protein binding
E0098655biological_processmonoatomic cation transmembrane transport
E0098685cellular_componentSchaffer collateral - CA1 synapse
E0098793cellular_componentpresynapse
E0098839cellular_componentpostsynaptic density membrane
E0098978cellular_componentglutamatergic synapse
E0099094molecular_functionligand-gated monoatomic cation channel activity
E0099505biological_processregulation of presynaptic membrane potential
E0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
E0099544cellular_componentperisynaptic space
E0106033cellular_componentspine synapse
E1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
E1905430biological_processcellular response to glycine
E1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues200
DetailsTRANSMEM: Helical
ChainResidueDetails
AILE529-TYR549
EGLY-227-ALA-207
AGLY602-ALA622
BILE529-TYR549
BGLY602-ALA622
CILE529-TYR549
CGLY602-ALA622
DILE529-TYR549
DGLY602-ALA622
EILE-300-TYR-280

site_idSWS_FT_FI2
Number of Residues155
DetailsTOPO_DOM: Cytoplasmic
ChainResidueDetails
AGLU550-SER576
ELEU-233-VAL-228
ALEU596-VAL601
BGLU550-SER576
BLEU596-VAL601
CGLU550-SER576
CLEU596-VAL601
DGLU550-SER576
DLEU596-VAL601
EGLU-279-SER-253

site_idSWS_FT_FI3
Number of Residues75
DetailsINTRAMEM: Helical; Pore-forming
ChainResidueDetails
ALEU577-SER592
BLEU577-SER592
CLEU577-SER592
DLEU577-SER592
ELEU-252-SER-237

site_idSWS_FT_FI4
Number of Residues10
DetailsINTRAMEM:
ChainResidueDetails
APRO593-SER595
BPRO593-SER595
CPRO593-SER595
DPRO593-SER595
EPRO-236-SER-234

site_idSWS_FT_FI5
Number of Residues870
DetailsTOPO_DOM: Extracellular
ChainResidueDetails
APHE623-TYR797
BPHE623-TYR797
CPHE623-TYR797
DPHE623-TYR797
EPHE-206-TYR-32

site_idSWS_FT_FI6
Number of Residues100
DetailsTRANSMEM: Helical; Name=M4
ChainResidueDetails
AILE798-SER818
BILE798-SER818
CILE798-SER818
DILE798-SER818
EILE-31-SER-11

site_idSWS_FT_FI7
Number of Residues15
DetailsBINDING: BINDING => ECO:0000269|PubMed:16483599
ChainResidueDetails
AASP456
DASP456
DPHE491
DTYR711
EASP-373
EPHE-338
ETYR-118
APHE491
ATYR711
BASP456
BPHE491
BTYR711
CASP456
CPHE491
CTYR711

site_idSWS_FT_FI8
Number of Residues5
DetailsBINDING:
ChainResidueDetails
AVAL484
BVAL484
CVAL484
DVAL484
EVAL-345

site_idSWS_FT_FI9
Number of Residues15
DetailsBINDING: BINDING => ECO:0000269|PubMed:25103405
ChainResidueDetails
AGLU486
DGLU486
DARG660
DARG661
EGLU-343
EARG-169
EARG-168
AARG660
AARG661
BGLU486
BARG660
BARG661
CGLU486
CARG660
CARG661

site_idSWS_FT_FI10
Number of Residues15
DetailsSITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405
ChainResidueDetails
AILE459
DILE459
DVAL666
DVAL758
EILE-370
EVAL-163
EVAL-71
AVAL666
AVAL758
BILE459
BVAL666
BVAL758
CILE459
CVAL666
CVAL758

site_idSWS_FT_FI11
Number of Residues5
DetailsSITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405
ChainResidueDetails
ALEU639
BLEU639
CLEU639
DLEU639
ELEU-190

site_idSWS_FT_FI12
Number of Residues5
DetailsMOD_RES: Phosphoserine; by PKC => ECO:0000269|PubMed:8848293
ChainResidueDetails
AASP668
BASP668
CASP668
DASP668
EASP-161

site_idSWS_FT_FI13
Number of Residues5
DetailsMOD_RES: Phosphoserine; by PKG => ECO:0000269|PubMed:8848293
ChainResidueDetails
ATYR702
BTYR702
CTYR702
DTYR702
ETYR-127

site_idSWS_FT_FI14
Number of Residues10
DetailsLIPID: S-palmitoyl cysteine => ECO:0000250
ChainResidueDetails
ASER595
EGLU-8
AGLU821
BSER595
BGLU821
CSER595
CGLU821
DSER595
DGLU821
ESER-234

site_idSWS_FT_FI15
Number of Residues5
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21317873
ChainResidueDetails
AGLU241
BGLU241
CGLU241
DGLU241
EGLU-588

site_idSWS_FT_FI16
Number of Residues5
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19946266, ECO:0000269|PubMed:21317873, ECO:0000269|PubMed:25103405
ChainResidueDetails
AASN355
BASN355
CASN355
DASN355
EASN-474

site_idSWS_FT_FI17
Number of Residues10
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AGLU391
ETHR-431
ATHR398
BGLU391
BTHR398
CGLU391
CTHR398
DGLU391
DTHR398
EGLU-438

site_idSWS_FT_FI18
Number of Residues400
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
AALA837-THR857
CGLY951-PHE971
CALA992-TYR1012
CTRP1036-LEU1056
DALA837-THR857
DGLY951-PHE971
DALA992-TYR1012
DTRP1036-LEU1056
EALA8-THR28
EGLY122-PHE142
EALA163-TYR183
AGLY951-PHE971
ETRP207-LEU227
AALA992-TYR1012
ATRP1036-LEU1056
BALA837-THR857
BGLY951-PHE971
BALA992-TYR1012
BTRP1036-LEU1056
CALA837-THR857

site_idSWS_FT_FI19
Number of Residues570
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails
ATHR858-LYS950
ETHR184-GLY206
ATHR1013-GLY1035
BTHR858-LYS950
BTHR1013-GLY1035
CTHR858-LYS950
CTHR1013-GLY1035
DTHR858-LYS950
DTHR1013-GLY1035
ETHR29-LYS121

site_idSWS_FT_FI20
Number of Residues95
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
ASER972-ASN991
BSER972-ASN991
CSER972-ASN991
DSER972-ASN991
ESER143-ASN162

219140

PDB entries from 2024-05-01

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