Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0033609 | biological_process | oxalate metabolic process |
| A | 0046564 | molecular_function | oxalate decarboxylase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0033609 | biological_process | oxalate metabolic process |
| B | 0046564 | molecular_function | oxalate decarboxylase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016831 | molecular_function | carboxy-lyase activity |
| C | 0033609 | biological_process | oxalate metabolic process |
| C | 0046564 | molecular_function | oxalate decarboxylase activity |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue ACT A 401 |
| Chain | Residue |
| A | MET84 |
| A | ARG92 |
| A | HIS95 |
| A | HIS97 |
| A | GLU101 |
| A | LEU153 |
| A | PHE155 |
| A | MN411 |
| A | HOH523 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 402 |
| Chain | Residue |
| A | VAL243 |
| A | ILE245 |
| A | ALA260 |
| A | ARG270 |
| A | GLU333 |
| A | TYR340 |
| A | HOH671 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue ACT A 403 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 404 |
| Chain | Residue |
| A | VAL222 |
| A | PRO225 |
| A | HOH673 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 405 |
| Chain | Residue |
| A | GLU117 |
| A | PRO135 |
| A | SER136 |
| A | HOH505 |
| A | HOH897 |
| C | PRO276 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 406 |
| Chain | Residue |
| A | GLY108 |
| A | GLY127 |
| A | GLU128 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 407 |
| Chain | Residue |
| A | GLN143 |
| A | ASN204 |
| A | GLN205 |
| A | HOH659 |
| C | THR355 |
| C | PHE356 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 408 |
| Chain | Residue |
| A | TYR104 |
| A | ILE106 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 409 |
| Chain | Residue |
| A | LYS87 |
| A | GLU146 |
| A | HOH676 |
| A | HOH788 |
| B | GLY13 |
| B | ASP14 |
| B | GLY16 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 410 |
| Chain | Residue |
| A | HIS273 |
| A | HIS275 |
| A | GLU280 |
| A | HIS319 |
| A | HOH571 |
| A | HOH577 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 411 |
| Chain | Residue |
| A | HIS95 |
| A | HIS97 |
| A | GLU101 |
| A | HIS140 |
| A | ACT401 |
| A | HOH523 |
| site_id | AD3 |
| Number of Residues | 10 |
| Details | binding site for residue ACT B 401 |
| Chain | Residue |
| B | MET84 |
| B | ARG92 |
| B | HIS95 |
| B | HIS97 |
| B | GLU101 |
| B | LEU153 |
| B | PHE155 |
| B | TYR200 |
| B | MN408 |
| B | HOH545 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue ACT B 402 |
| Chain | Residue |
| B | VAL243 |
| B | ILE245 |
| B | ALA260 |
| B | ARG270 |
| B | GLU333 |
| B | TYR340 |
| B | HOH646 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue ACT B 403 |
| Chain | Residue |
| B | HIS56 |
| B | ARG58 |
| B | ASN163 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue ACT B 404 |
| Chain | Residue |
| B | TYR104 |
| B | MET105 |
| B | ILE106 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 405 |
| Chain | Residue |
| B | ASP41 |
| B | HIS42 |
| B | GLY43 |
| B | HOH509 |
| B | HOH631 |
| site_id | AD8 |
| Number of Residues | 1 |
| Details | binding site for residue GOL B 406 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue MN B 407 |
| Chain | Residue |
| B | HIS273 |
| B | HIS275 |
| B | GLU280 |
| B | HIS319 |
| B | HOH558 |
| B | HOH568 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue MN B 408 |
| Chain | Residue |
| B | HIS95 |
| B | HIS97 |
| B | GLU101 |
| B | HIS140 |
| B | ACT401 |
| B | HOH545 |
| site_id | AE2 |
| Number of Residues | 9 |
| Details | binding site for residue ACT C 401 |
| Chain | Residue |
| C | HIS95 |
| C | HIS97 |
| C | GLU101 |
| C | LEU153 |
| C | PHE155 |
| C | MN406 |
| C | HOH523 |
| C | MET84 |
| C | ARG92 |
| site_id | AE3 |
| Number of Residues | 8 |
| Details | binding site for residue ACT C 402 |
| Chain | Residue |
| C | VAL243 |
| C | ILE245 |
| C | ALA260 |
| C | VAL262 |
| C | ARG270 |
| C | GLU333 |
| C | TYR340 |
| C | HOH641 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue MPD C 403 |
| Chain | Residue |
| C | TYR104 |
| C | ILE106 |
| C | HOH763 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue MPD C 404 |
| Chain | Residue |
| C | LYS87 |
| C | HOH511 |
| C | HOH667 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue MN C 405 |
| Chain | Residue |
| C | HIS273 |
| C | HIS275 |
| C | GLU280 |
| C | HIS319 |
| C | HOH585 |
| C | HOH586 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue MN C 406 |
| Chain | Residue |
| C | HIS95 |
| C | HIS97 |
| C | GLU101 |
| C | HIS140 |
| C | ACT401 |
| C | HOH523 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 426 |
| Details | Domain: {"description":"Cupin type-1 1","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 423 |
| Details | Domain: {"description":"Cupin type-1 2","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 69 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"12056897","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12056897","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 231 |
| Chain | Residue | Details |
| A | ARG92 | attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond donor |
| A | HIS95 | metal ligand |
| A | HIS97 | metal ligand |
| A | GLU101 | metal ligand |
| A | HIS140 | metal ligand |
| A | GLU162 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 231 |
| Chain | Residue | Details |
| B | ARG92 | attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond donor |
| B | HIS95 | metal ligand |
| B | HIS97 | metal ligand |
| B | GLU101 | metal ligand |
| B | HIS140 | metal ligand |
| B | GLU162 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 6 |
| Details | M-CSA 231 |
| Chain | Residue | Details |
| C | ARG92 | attractive charge-charge interaction, electrostatic stabiliser, hydrogen bond donor |
| C | HIS95 | metal ligand |
| C | HIS97 | metal ligand |
| C | GLU101 | metal ligand |
| C | HIS140 | metal ligand |
| C | GLU162 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
