5VFW

An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004859	molecular_function	phospholipase inhibitor activity
A	0005509	molecular_function	calcium ion binding
A	0005544	molecular_function	calcium-dependent phospholipid binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Peptide: {"description":"Annexin Ac2-26","featureId":"PRO_0000454556","evidences":[{"source":"PubMed","id":"22879591","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"3303336","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by TRPM7","evidences":[{"source":"PubMed","id":"15485879","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine; by EGFR","evidences":[{"source":"PubMed","id":"2457390","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Cross-link: {"description":"Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-?)"}

Chain

Residue

Details

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