5VCU
Crystal structure of ras-related c3 botulinum toxin substrate 1 isoform x2 from Naegleria fowleri in complex with GDP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005525 | molecular_function | GTP binding |
| A | 0007264 | biological_process | small GTPase-mediated signal transduction |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
| B | 0007264 | biological_process | small GTPase-mediated signal transduction |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | binding site for residue GDP A 301 |
| Chain | Residue |
| A | ALA13 |
| A | LYS116 |
| A | ASP118 |
| A | LEU119 |
| A | SER158 |
| A | ALA159 |
| A | LYS160 |
| A | MG302 |
| A | HOH414 |
| A | HOH421 |
| A | HOH426 |
| A | VAL14 |
| A | HOH432 |
| A | HOH441 |
| A | HOH449 |
| A | HOH452 |
| A | HOH472 |
| A | HOH519 |
| A | HOH536 |
| A | HOH563 |
| A | GLY15 |
| A | LYS16 |
| A | THR17 |
| A | ALA18 |
| A | PHE28 |
| A | GLU62 |
| A | ASP63 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 302 |
| Chain | Residue |
| A | THR17 |
| A | THR35 |
| A | GDP301 |
| A | HOH414 |
| A | HOH432 |
| A | HOH441 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | binding site for residue GDP B 301 |
| Chain | Residue |
| B | ALA13 |
| B | VAL14 |
| B | GLY15 |
| B | LYS16 |
| B | THR17 |
| B | ALA18 |
| B | PHE28 |
| B | VAL33 |
| B | LYS116 |
| B | ASP118 |
| B | LEU119 |
| B | SER158 |
| B | ALA159 |
| B | LYS160 |
| B | MG302 |
| B | HOH427 |
| B | HOH430 |
| B | HOH437 |
| B | HOH439 |
| B | HOH444 |
| B | HOH463 |
| B | HOH468 |
| B | HOH494 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 302 |
| Chain | Residue |
| B | THR17 |
| B | GDP301 |
| B | HOH430 |
| B | HOH439 |
| B | HOH463 |
| B | HOH495 |
