Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008270 | molecular_function | zinc ion binding |
B | 0004222 | molecular_function | metalloendopeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ZN A 501 |
Chain | Residue |
A | HIS223 |
A | HIS227 |
A | GLU262 |
A | 90M502 |
site_id | AC2 |
Number of Residues | 12 |
Details | binding site for residue 90M A 502 |
Chain | Residue |
A | THR220 |
A | GLU224 |
A | GLU262 |
A | TYR366 |
A | ZN501 |
A | HOH650 |
A | HOH731 |
A | ILE161 |
A | PHE163 |
A | THR193 |
A | PHE194 |
A | THR215 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue ZN B 501 |
Chain | Residue |
B | HIS223 |
B | HIS227 |
B | GLU262 |
B | 90M502 |
site_id | AC4 |
Number of Residues | 11 |
Details | binding site for residue 90M B 502 |
Chain | Residue |
B | ILE161 |
B | PHE163 |
B | THR193 |
B | PHE194 |
B | THR215 |
B | THR220 |
B | GLU224 |
B | GLU262 |
B | TYR366 |
B | ZN501 |
B | HOH662 |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TLAHELIHAG |
Chain | Residue | Details |
A | THR220-GLY229 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLU224 | |
B | GLU224 | |
Chain | Residue | Details |
A | HIS223 | |
A | HIS227 | |
B | HIS223 | |
B | HIS227 | |
Chain | Residue | Details |
A | GLU262 | |
B | GLU262 | |
Chain | Residue | Details |
A | ARG363 | |
A | TYR366 | |
B | ARG363 | |
B | TYR366 | |