Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5V6N

Crystal Structure of the highly open channel-stabilized mutant C27S + K33C + I9'A + N21'C of GLIC under reducing conditions.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0005267	molecular_function	potassium channel activity
A	0005272	molecular_function	sodium channel activity
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006813	biological_process	potassium ion transport
A	0006814	biological_process	sodium ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0035725	biological_process	sodium ion transmembrane transport
A	0042802	molecular_function	identical protein binding
A	0071805	biological_process	potassium ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0005267	molecular_function	potassium channel activity
B	0005272	molecular_function	sodium channel activity
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0006813	biological_process	potassium ion transport
B	0006814	biological_process	sodium ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0035725	biological_process	sodium ion transmembrane transport
B	0042802	molecular_function	identical protein binding
B	0071805	biological_process	potassium ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0005267	molecular_function	potassium channel activity
C	0005272	molecular_function	sodium channel activity
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0006813	biological_process	potassium ion transport
C	0006814	biological_process	sodium ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0035725	biological_process	sodium ion transmembrane transport
C	0042802	molecular_function	identical protein binding
C	0071805	biological_process	potassium ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0005267	molecular_function	potassium channel activity
D	0005272	molecular_function	sodium channel activity
D	0005886	cellular_component	plasma membrane
D	0006811	biological_process	monoatomic ion transport
D	0006813	biological_process	potassium ion transport
D	0006814	biological_process	sodium ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0035725	biological_process	sodium ion transmembrane transport
D	0042802	molecular_function	identical protein binding
D	0071805	biological_process	potassium ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0005267	molecular_function	potassium channel activity
E	0005272	molecular_function	sodium channel activity
E	0005886	cellular_component	plasma membrane
E	0006811	biological_process	monoatomic ion transport
E	0006813	biological_process	potassium ion transport
E	0006814	biological_process	sodium ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0035725	biological_process	sodium ion transmembrane transport
E	0042802	molecular_function	identical protein binding
E	0071805	biological_process	potassium ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue LMT C 401

Chain	Residue
B	LMT402
C	ALA237
C	ILE240

site_id	AC2
Number of Residues	3
Details	binding site for residue LMT A 402

Chain	Residue
A	ILE240
A	LEU241
B	ALA234

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 A 403

Chain	Residue
A	ARG293
A	ARG296
E	TYR278

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 B 401

Chain	Residue
B	TYR278
B	GLU282
C	ARG293
C	ARG296

site_id	AC5
Number of Residues	3
Details	binding site for residue LMT B 402

Chain	Residue
B	ALA237
C	ALA234
C	LMT401

site_id	AC6
Number of Residues	4
Details	binding site for residue SO4 B 403

Chain	Residue
A	TYR278
A	GLU282
B	ARG293
B	ARG296

site_id	AC7
Number of Residues	4
Details	binding site for residue LMT D 401

Chain	Residue
D	ALA237
D	ILE240
E	ALA233
E	ALA234

site_id	AC8
Number of Residues	4
Details	binding site for residue SO4 D 402

Chain	Residue
C	TYR278
C	GLU282
D	ARG293
D	ARG296

site_id	AC9
Number of Residues	2
Details	binding site for residue LMT E 401

Chain	Residue
E	ALA233
E	ALA237

site_id	AD1
Number of Residues	4
Details	binding site for residue SO4 E 402

Chain	Residue
D	TYR278
D	GLU282
E	ARG293
E	ARG296

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	530
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	20
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	35
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)