Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

5V5S

multi-drug efflux; membrane transport; RND superfamily; Drug resistance

Functional Information from GO Data
ChainGOidnamespacecontents
A0005216molecular_functionmonoatomic ion channel activity
A0005515molecular_functionprotein binding
A0009279cellular_componentcell outer membrane
A0009410biological_processresponse to xenobiotic stimulus
A0009636biological_processresponse to toxic substance
A0015125molecular_functionbile acid transmembrane transporter activity
A0015288molecular_functionporin activity
A0015562molecular_functionefflux transmembrane transporter activity
A0015721biological_processbile acid and bile salt transport
A0016020cellular_componentmembrane
A0019867cellular_componentouter membrane
A0034220biological_processmonoatomic ion transmembrane transport
A0042802molecular_functionidentical protein binding
A0042930biological_processenterobactin transport
A0042931molecular_functionenterobactin transmembrane transporter activity
A0046677biological_processresponse to antibiotic
A0055085biological_processtransmembrane transport
A0098567cellular_componentperiplasmic side of plasma membrane
A0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
A1990196cellular_componentMacAB-TolC complex
A1990281cellular_componentefflux pump complex
A1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
B0005216molecular_functionmonoatomic ion channel activity
B0005515molecular_functionprotein binding
B0009279cellular_componentcell outer membrane
B0009410biological_processresponse to xenobiotic stimulus
B0009636biological_processresponse to toxic substance
B0015125molecular_functionbile acid transmembrane transporter activity
B0015288molecular_functionporin activity
B0015562molecular_functionefflux transmembrane transporter activity
B0015721biological_processbile acid and bile salt transport
B0016020cellular_componentmembrane
B0019867cellular_componentouter membrane
B0034220biological_processmonoatomic ion transmembrane transport
B0042802molecular_functionidentical protein binding
B0042930biological_processenterobactin transport
B0042931molecular_functionenterobactin transmembrane transporter activity
B0046677biological_processresponse to antibiotic
B0055085biological_processtransmembrane transport
B0098567cellular_componentperiplasmic side of plasma membrane
B0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
B1990196cellular_componentMacAB-TolC complex
B1990281cellular_componentefflux pump complex
B1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
C0005216molecular_functionmonoatomic ion channel activity
C0005515molecular_functionprotein binding
C0009279cellular_componentcell outer membrane
C0009410biological_processresponse to xenobiotic stimulus
C0009636biological_processresponse to toxic substance
C0015125molecular_functionbile acid transmembrane transporter activity
C0015288molecular_functionporin activity
C0015562molecular_functionefflux transmembrane transporter activity
C0015721biological_processbile acid and bile salt transport
C0016020cellular_componentmembrane
C0019867cellular_componentouter membrane
C0034220biological_processmonoatomic ion transmembrane transport
C0042802molecular_functionidentical protein binding
C0042930biological_processenterobactin transport
C0042931molecular_functionenterobactin transmembrane transporter activity
C0046677biological_processresponse to antibiotic
C0055085biological_processtransmembrane transport
C0098567cellular_componentperiplasmic side of plasma membrane
C0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
C1990196cellular_componentMacAB-TolC complex
C1990281cellular_componentefflux pump complex
C1990961biological_processxenobiotic detoxification by transmembrane export across the plasma membrane
D0016020cellular_componentmembrane
D0022857molecular_functiontransmembrane transporter activity
D0055085biological_processtransmembrane transport
E0016020cellular_componentmembrane
E0022857molecular_functiontransmembrane transporter activity
E0055085biological_processtransmembrane transport
F0016020cellular_componentmembrane
F0022857molecular_functiontransmembrane transporter activity
F0055085biological_processtransmembrane transport
G0016020cellular_componentmembrane
G0022857molecular_functiontransmembrane transporter activity
G0055085biological_processtransmembrane transport
H0016020cellular_componentmembrane
H0022857molecular_functiontransmembrane transporter activity
H0055085biological_processtransmembrane transport
I0016020cellular_componentmembrane
I0022857molecular_functiontransmembrane transporter activity
I0055085biological_processtransmembrane transport
J0005515molecular_functionprotein binding
J0005886cellular_componentplasma membrane
J0009410biological_processresponse to xenobiotic stimulus
J0009636biological_processresponse to toxic substance
J0015125molecular_functionbile acid transmembrane transporter activity
J0015562molecular_functionefflux transmembrane transporter activity
J0015567molecular_functionalkane transmembrane transporter activity
J0015721biological_processbile acid and bile salt transport
J0015895biological_processalkane transport
J0015908biological_processfatty acid transport
J0016020cellular_componentmembrane
J0022857molecular_functiontransmembrane transporter activity
J0042802molecular_functionidentical protein binding
J0042908biological_processxenobiotic transport
J0042910molecular_functionxenobiotic transmembrane transporter activity
J0042930biological_processenterobactin transport
J0042931molecular_functionenterobactin transmembrane transporter activity
J0046677biological_processresponse to antibiotic
J0055085biological_processtransmembrane transport
J0098567cellular_componentperiplasmic side of plasma membrane
J0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
J1990281cellular_componentefflux pump complex
K0005515molecular_functionprotein binding
K0005886cellular_componentplasma membrane
K0009410biological_processresponse to xenobiotic stimulus
K0009636biological_processresponse to toxic substance
K0015125molecular_functionbile acid transmembrane transporter activity
K0015562molecular_functionefflux transmembrane transporter activity
K0015567molecular_functionalkane transmembrane transporter activity
K0015721biological_processbile acid and bile salt transport
K0015895biological_processalkane transport
K0015908biological_processfatty acid transport
K0016020cellular_componentmembrane
K0022857molecular_functiontransmembrane transporter activity
K0042802molecular_functionidentical protein binding
K0042908biological_processxenobiotic transport
K0042910molecular_functionxenobiotic transmembrane transporter activity
K0042930biological_processenterobactin transport
K0042931molecular_functionenterobactin transmembrane transporter activity
K0046677biological_processresponse to antibiotic
K0055085biological_processtransmembrane transport
K0098567cellular_componentperiplasmic side of plasma membrane
K0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
K1990281cellular_componentefflux pump complex
L0005515molecular_functionprotein binding
L0005886cellular_componentplasma membrane
L0009410biological_processresponse to xenobiotic stimulus
L0009636biological_processresponse to toxic substance
L0015125molecular_functionbile acid transmembrane transporter activity
L0015562molecular_functionefflux transmembrane transporter activity
L0015567molecular_functionalkane transmembrane transporter activity
L0015721biological_processbile acid and bile salt transport
L0015895biological_processalkane transport
L0015908biological_processfatty acid transport
L0016020cellular_componentmembrane
L0022857molecular_functiontransmembrane transporter activity
L0042802molecular_functionidentical protein binding
L0042908biological_processxenobiotic transport
L0042910molecular_functionxenobiotic transmembrane transporter activity
L0042930biological_processenterobactin transport
L0042931molecular_functionenterobactin transmembrane transporter activity
L0046677biological_processresponse to antibiotic
L0055085biological_processtransmembrane transport
L0098567cellular_componentperiplasmic side of plasma membrane
L0140330biological_processxenobiotic detoxification by transmembrane export across the cell outer membrane
L1990281cellular_componentefflux pump complex
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues33
DetailsTransmembrane: {"description":"Beta stranded; Name=S1"}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues81
DetailsTopological domain: {"description":"Extracellular"}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues39
DetailsTransmembrane: {"description":"Beta stranded; Name=S2"}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues30
DetailsTransmembrane: {"description":"Beta stranded; Name=S4"}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues84
DetailsRegion: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues45
DetailsCompositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues444
DetailsCoiled coil: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues372
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"15919996","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues54
DetailsTransmembrane: {"description":"Helical; Name=1"}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues1932
DetailsTopological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"15919996","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues57
DetailsTransmembrane: {"description":"Helical; Name=2"}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues57
DetailsTransmembrane: {"description":"Helical; Name=3"}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues63
DetailsTransmembrane: {"description":"Helical; Name=4"}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues54
DetailsTransmembrane: {"description":"Helical; Name=5"}
ChainResidueDetails
site_idSWS_FT_FI15
Number of Residues72
DetailsTransmembrane: {"description":"Helical; Name=6"}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues48
DetailsTransmembrane: {"description":"Helical; Name=7"}
ChainResidueDetails
site_idSWS_FT_FI17
Number of Residues48
DetailsTransmembrane: {"description":"Helical; Name=8"}
ChainResidueDetails
site_idSWS_FT_FI18
Number of Residues57
DetailsTransmembrane: {"description":"Helical; Name=9"}
ChainResidueDetails
site_idSWS_FT_FI19
Number of Residues54
DetailsTransmembrane: {"description":"Helical; Name=10"}
ChainResidueDetails
site_idSWS_FT_FI20
Number of Residues57
DetailsTransmembrane: {"description":"Helical; Name=11"}
ChainResidueDetails
site_idSWS_FT_FI21
Number of Residues57
DetailsTransmembrane: {"description":"Helical; Name=12"}
ChainResidueDetails

247947

PDB entries from 2026-01-21

PDB statisticsPDBj update infoContact PDBjnumon