5V2L

Mevalonate diphosphate mediated ATP binding mechanism of the mevalonate diphosphate decarboxylase from Enterococcus faecalis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004163	molecular_function	diphosphomevalonate decarboxylase activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006629	biological_process	lipid metabolic process
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0019287	biological_process	isopentenyl diphosphate biosynthetic process, mevalonate pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue ATP A 401

Chain	Residue
A	THR42
A	SER106
A	GLY109
A	SER191
A	HOH504
A	HOH512
A	PHE57
A	LEU59
A	GLN68
A	VAL72
A	SER93
A	ASN95
A	ALA104
A	SER105

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site_id	AC2
Number of Residues	8
Details	binding site for residue PO4 A 402

Chain	Residue
A	TYR17
A	LYS20
A	ILE26
A	LYS71
A	SER138
A	GLY139
A	ARG192
A	HOH502

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