5V0V

Crystal structure of Equine Serum Albumin complex with etodolac

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005504	molecular_function	fatty acid binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0008289	molecular_function	lipid binding
A	0009267	biological_process	cellular response to starvation
A	0015643	molecular_function	toxic substance binding
A	0019825	molecular_function	oxygen binding
A	0030170	molecular_function	pyridoxal phosphate binding
A	0031667	biological_process	response to nutrient levels
A	0032991	cellular_component	protein-containing complex
A	0046872	molecular_function	metal ion binding
A	0051902	biological_process	negative regulation of mitochondrial depolarization
A	0072732	biological_process	cellular response to calcium ion starvation
A	1903981	molecular_function	enterobactin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue TRS A 601

Chain	Residue
A	ASN390
A	ARG409
A	TYR410
A	SER488

---

site_id	AC2
Number of Residues	2
Details	binding site for residue TRS A 602

Chain	Residue
A	LYS412
A	LYS540

---

site_id	AC3
Number of Residues	2
Details	binding site for residue TRS A 603

Chain	Residue
A	LYS17
A	ASP131

---

site_id	AC4
Number of Residues	7
Details	binding site for residue TRS A 604

Chain	Residue
A	ARG217
A	LYS221
A	ASN450
A	HIS451
A	HOH714
A	HOH777
A	LYS194

---

site_id	AC5
Number of Residues	6
Details	binding site for residue SO4 A 605

Chain	Residue
A	ASN111
A	GLU265
A	HIS266
A	ASP268
A	SER269
A	HOH727

---

site_id	AC6
Number of Residues	4
Details	binding site for residue SO4 A 606

Chain	Residue
A	ALA303
A	LEU304
A	ALA305
A	ARG336

---

site_id	AC7
Number of Residues	3
Details	binding site for residue SO4 A 607

Chain	Residue
A	GLY206
A	GLU207
A	ARG208

---

site_id	AC8
Number of Residues	3
Details	binding site for residue SO4 A 608

Chain	Residue
A	ALA321
A	LYS322
A	ASP323

---

site_id	AC9
Number of Residues	2
Details	binding site for residue SO4 A 609

Chain	Residue
A	LYS180
A	ARG187

---

site_id	AD1
Number of Residues	3
Details	binding site for residue SO4 A 610

Chain	Residue
A	SER65
A	GLU95
A	PRO96

---

site_id	AD2
Number of Residues	5
Details	binding site for residue SO4 A 611

Chain	Residue
A	LEU14
A	GLY15
A	GLU16
A	LYS17
A	HOH730

---

site_id	AD3
Number of Residues	11
Details	binding site for residue 8QP A 612

Chain	Residue
A	TYR149
A	GLU195
A	LEU218
A	LEU237
A	HIS241
A	ARG256
A	SER286
A	ILE289
A	ALA290
A	GLU291
A	HOH701

---

site_id	AD4
Number of Residues	6
Details	binding site for residue 8QP A 613

Chain	Residue
A	ARG208
A	LYS211
A	VAL215
A	SER231
A	GLY327
A	8QS614

---

site_id	AD5
Number of Residues	8
Details	binding site for residue 8QS A 614

Chain	Residue
A	ARG208
A	ALA349
A	LYS350
A	SER479
A	LEU480
A	8QP613
A	HOH731
A	HOH776

---

site_id	AD6
Number of Residues	6
Details	binding site for residue 8QS A 615

Chain	Residue
A	LEU115
A	TYR137
A	ARG144
A	HIS145
A	LEU181
A	ILE188

---

Functional Information from PROSITE/UniProt

site_id	PS00212
Number of Residues	25
Details	ALBUMIN_1 Albumin domain signature. YkadfteCCpaDdklaCLipkldaL

Chain	Residue	Details
A	TYR160-LEU184
A	TYR352-PHE376
A	PHE550-LEU574

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	192
Details	Domain: {"description":"Albumin 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00769","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	197
Details	Domain: {"description":"Albumin 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00769","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P02770","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P02769","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28567254","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IIH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	5
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P02770","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P07724","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---