5V0P
Crystal Structure of Beta-ketoacyl-ACP synthase III-2 (FabH2) (C113A) from Vibrio Cholerae co-crystallized with octanoyl-CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0030497 | biological_process | fatty acid elongation |
| A | 0033818 | molecular_function | beta-ketoacyl-acyl-carrier-protein synthase III activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0030497 | biological_process | fatty acid elongation |
| B | 0033818 | molecular_function | beta-ketoacyl-acyl-carrier-protein synthase III activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 401 |
| Chain | Residue |
| A | GLU244 |
| A | ASP246 |
| A | ASP305 |
| A | HOH609 |
| A | HOH615 |
| A | HOH649 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | binding site for residue CO8 A 402 |
| Chain | Residue |
| A | ALA112 |
| A | ALA113 |
| A | ARG152 |
| A | ASP153 |
| A | VAL156 |
| A | PHE158 |
| A | LEU191 |
| A | PHE212 |
| A | GLY216 |
| A | LYS217 |
| A | ILE219 |
| A | HIS251 |
| A | ALA253 |
| A | ASN254 |
| A | ASN281 |
| A | SER283 |
| A | PHE311 |
| A | GLY312 |
| A | ALA313 |
| A | HOH511 |
| B | ILE88 |
| A | THR31 |
| A | TRP35 |
| A | ARG39 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 401 |
| Chain | Residue |
| B | GLU244 |
| B | ASP246 |
| B | ASP305 |
| B | HOH613 |
| B | HOH627 |
| B | HOH648 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | binding site for residue CO8 B 402 |
| Chain | Residue |
| A | ILE88 |
| B | THR31 |
| B | TRP35 |
| B | ARG39 |
| B | ALA113 |
| B | LEU143 |
| B | ARG152 |
| B | ASP153 |
| B | VAL156 |
| B | LEU191 |
| B | PHE212 |
| B | GLY216 |
| B | ILE219 |
| B | HIS251 |
| B | ALA253 |
| B | ASN254 |
| B | ILE257 |
| B | ASN281 |
| B | SER283 |
| B | PHE311 |
| B | GLY312 |
| B | ALA313 |
| B | HOH510 |
| B | HOH549 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Region: {"description":"ACP-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_01815","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01815","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
