Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0008446 | molecular_function | GDP-mannose 4,6-dehydratase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019673 | biological_process | GDP-mannose metabolic process |
| A | 0042350 | biological_process | GDP-L-fucose biosynthetic process |
| A | 0042351 | biological_process | 'de novo' GDP-L-fucose biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue GDP A 401 |
| Chain | Residue |
| A | VAL123 |
| A | ASN251 |
| A | ALA254 |
| A | ARG256 |
| A | VAL290 |
| A | TYR332 |
| A | ARG334 |
| A | GLU337 |
| A | HOH506 |
| A | HOH522 |
| A | HOH545 |
| A | GLU166 |
| A | HOH557 |
| A | HOH584 |
| A | HOH598 |
| A | ASN217 |
| A | THR226 |
| A | PHE227 |
| A | VAL228 |
| A | LYS231 |
| A | LEU249 |
| A | GLY250 |
| site_id | AC2 |
| Number of Residues | 40 |
| Details | binding site for residue NAP A 402 |
| Chain | Residue |
| A | GLY40 |
| A | THR42 |
| A | GLY43 |
| A | GLN44 |
| A | ASP45 |
| A | ARG65 |
| A | ARG66 |
| A | SER67 |
| A | SER68 |
| A | ASN71 |
| A | ASP95 |
| A | LEU96 |
| A | LEU117 |
| A | ALA118 |
| A | ALA119 |
| A | SER121 |
| A | TYR132 |
| A | VAL136 |
| A | ALA162 |
| A | SER163 |
| A | THR164 |
| A | TYR188 |
| A | LYS192 |
| A | LEU215 |
| A | ASN217 |
| A | HIS218 |
| A | ARG223 |
| A | HOH502 |
| A | HOH504 |
| A | HOH509 |
| A | HOH537 |
| A | HOH539 |
| A | HOH555 |
| A | HOH566 |
| A | HOH567 |
| A | HOH569 |
| A | HOH586 |
| A | HOH601 |
| A | HOH604 |
| A | HOH628 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue MPD A 403 |
| Chain | Residue |
| A | GLU178 |
| A | THR179 |
| A | TYR183 |
| A | TYR196 |
| A | HOH532 |
| A | HOH578 |
| A | HOH589 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue MPD A 404 |
| Chain | Residue |
| A | GLU178 |
| A | THR179 |
| A | THR180 |
| A | PRO181 |
| A | PHE182 |
| A | TYR196 |
| A | HOH609 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue MPD A 405 |
| Chain | Residue |
| A | ALA150 |
| A | ALA150 |
| A | CYS151 |
| A | CYS151 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 406 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. PqkettpfypRspYACAKLYSyWIVvNYR |
| Chain | Residue | Details |
| A | PRO175-ARG203 | |
