Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue FAD A 401 |
| Chain | Residue |
| A | GLY10 |
| A | GLY77 |
| A | ILE78 |
| A | VAL79 |
| A | THR107 |
| A | GLY108 |
| A | TYR111 |
| A | CYS133 |
| A | ASP134 |
| A | VAL239 |
| A | GLY272 |
| A | PRO11 |
| A | ASP273 |
| A | ARG280 |
| A | GLN281 |
| A | ILE282 |
| A | ALA12 |
| A | GLU31 |
| A | GLN32 |
| A | GLY37 |
| A | GLN38 |
| A | THR42 |
| A | ASN47 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 A 402 |
| Chain | Residue |
| A | THR284 |
| A | THR284 |
| A | GLY287 |
| A | GLY287 |
| A | ASP288 |
| A | ASP288 |
| A | ILE291 |
| A | ILE291 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 403 |
| Chain | Residue |
| A | GLY149 |
| A | ASP150 |
| A | SER151 |
| A | ARG176 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 404 |
| Chain | Residue |
| A | ASP259 |
| A | HIS260 |
| A | ASP278 |
| A | HOH503 |
Functional Information from PROSITE/UniProt
| site_id | PS00573 |
| Number of Residues | 21 |
| Details | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CavCDGaf..FrdqdLlVVGGGD |
| Chain | Residue | Details |
| A | CYS130-ASP150 | |
5UWY
