5UVX
BRD4 Bromodomain 2 with A-1359643
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue 8NM A 501 |
| Chain | Residue |
| A | TRP374 |
| A | ASN433 |
| A | HIS437 |
| A | MET442 |
| A | HOH604 |
| B | ASP436 |
| B | HOH601 |
| A | PRO375 |
| A | PHE376 |
| A | LYS378 |
| A | PRO379 |
| A | VAL380 |
| A | ASP381 |
| A | LEU385 |
| A | LEU387 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue 8NM B 501 |
| Chain | Residue |
| A | TRP374 |
| B | TRP374 |
| B | PRO375 |
| B | PHE376 |
| B | LYS378 |
| B | PRO379 |
| B | VAL380 |
| B | ASP381 |
| B | LEU385 |
| B | ASN433 |
| B | MET442 |
| B | HOH606 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Site: {"description":"Acetylated histone binding","evidences":[{"source":"PubMed","id":"22464331","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
