Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 41 |
| Details | binding site for residue FAD A 400 |
| Chain | Residue |
| A | ILE13 |
| A | GLY38 |
| A | GLN40 |
| A | GLY42 |
| A | GLY43 |
| A | ALA44 |
| A | LEU45 |
| A | THR48 |
| A | ASN53 |
| A | ASP85 |
| A | VAL86 |
| A | GLY14 |
| A | ALA113 |
| A | MET114 |
| A | GLY115 |
| A | THR136 |
| A | CYS140 |
| A | ARG245 |
| A | LEU248 |
| A | GLY279 |
| A | ASP280 |
| A | ARG287 |
| A | SER15 |
| A | GLN288 |
| A | ALA289 |
| A | ALA292 |
| A | HOH515 |
| A | HOH518 |
| A | HOH541 |
| A | HOH565 |
| A | HOH579 |
| A | HOH594 |
| A | HOH596 |
| A | GLY16 |
| A | HOH632 |
| A | HOH644 |
| A | PRO17 |
| A | ALA18 |
| A | TYR25 |
| A | PHE36 |
| A | GLU37 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | ARG71 |
| A | ARG219 |
| A | HOH508 |
| A | HOH564 |
| A | HOH638 |
| A | HOH658 |
| A | HOH659 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | HIS8 |
| A | ARG82 |
| A | HIS105 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | PRO124 |
| A | GLY125 |
| A | GLU126 |
| A | GLU127 |
| A | ALA128 |
| A | HOH583 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 404 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | ALA117 |
| A | ARG245 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | HIS177 |
| A | GLU181 |
| A | ARG183 |
| A | HOH574 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 407 |
| Chain | Residue |
| A | ASP256 |
| A | ASP257 |
| A | LYS262 |
| A | HOH635 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 408 |
| Chain | Residue |
| A | ASP157 |
| A | SER158 |
| A | GLY241 |
| A | HOH505 |
| A | HOH517 |
| A | HOH617 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 409 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 410 |
| Chain | Residue |
| A | VAL263 |
| A | GLN264 |
| A | GLY265 |
| A | HOH634 |
| A | HOH704 |
Functional Information from PROSITE/UniProt
| site_id | PS00573 |
| Number of Residues | 21 |
| Details | PYRIDINE_REDOX_2 Pyridine nucleotide-disulphide oxidoreductases class-II active site. CatCDGff..FrdqdIvVVGGGD |
| Chain | Residue | Details |
| A | CYS137-ASP157 | |
