Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 8MY A 901 |
| Chain | Residue |
| A | LEU579 |
| A | ASN678 |
| A | LEU680 |
| A | HOH1032 |
| A | HOH1065 |
| A | GLN626 |
| A | GLU627 |
| A | PHE628 |
| A | VAL629 |
| A | LYS630 |
| A | GLY632 |
| A | SER633 |
| A | LYS677 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 902 |
| Chain | Residue |
| A | ASN673 |
| A | ARG715 |
| A | TRP718 |
| A | GOL906 |
| A | HOH1123 |
| A | HOH1141 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 903 |
| Chain | Residue |
| A | ARG683 |
| A | PHE694 |
| A | HOH1015 |
| A | HOH1113 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 904 |
| Chain | Residue |
| A | LEU783 |
| A | ASN786 |
| A | PRO796 |
| A | ALA800 |
| A | ASP804 |
| A | HOH1013 |
| A | HOH1082 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 905 |
| Chain | Residue |
| A | PRO721 |
| A | TYR766 |
| A | ARG769 |
| A | HOH1025 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 906 |
| Chain | Residue |
| A | THR555 |
| A | ASN673 |
| A | ASN678 |
| A | ARG715 |
| A | GOL902 |
| A | HOH1011 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 907 |
| Chain | Residue |
| A | ALA781 |
| A | ASN782 |
| A | ASN785 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 908 |
| Chain | Residue |
| A | HIS606 |
| A | HOH1219 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Site: {"description":"Breakpoint for translocation to form PCM1-JAK2 fusion protein"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
