5UR5

PYR1 bound to the rationally designed agonist 4m

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004864	molecular_function	protein phosphatase inhibitor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005773	cellular_component	vacuole
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0009705	cellular_component	plant-type vacuole membrane
A	0009738	biological_process	abscisic acid-activated signaling pathway
A	0010427	molecular_function	abscisic acid binding
A	0019207	molecular_function	kinase regulator activity
A	0038023	molecular_function	signaling receptor activity
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0044389	molecular_function	ubiquitin-like protein ligase binding
A	0062049	cellular_component	protein phosphatase inhibitor complex
A	1902584	biological_process	positive regulation of response to water deprivation

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SO4 A 201

Chain	Residue
A	GLN36
A	GLN169
A	ARG180
A	ASN181
A	HOH377
A	HOH385

---

site_id	AC2
Number of Residues	6
Details	binding site for residue SO4 A 202

Chain	Residue
A	HOH302
A	HOH349
A	HOH391
A	SER47
A	ARG51
A	LYS54

---

site_id	AC3
Number of Residues	6
Details	binding site for residue SO4 A 203

Chain	Residue
A	GLY113
A	GLY113
A	HOH311
A	HOH311
A	HOH400
A	HOH400

---

site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 A 204

Chain	Residue
A	ARG37
A	HIS39
A	HIS39
A	ARG134
A	TRP136
A	HOH315
A	HOH320

---

site_id	AC5
Number of Residues	6
Details	binding site for residue SO4 A 205

Chain	Residue
A	GLU102
A	GLU102
A	ARG103
A	ARG103
A	GOL208
A	GOL208

---

site_id	AC6
Number of Residues	3
Details	binding site for residue SO4 A 206

Chain	Residue
A	ARG104
A	ARG128
A	GOL208

---

site_id	AC7
Number of Residues	13
Details	binding site for residue 8KP A 207

Chain	Residue
A	LYS59
A	ILE62
A	VAL81
A	VAL83
A	ALA89
A	SER92
A	GLU94
A	PHE108
A	HIS115
A	TYR120
A	PHE159
A	HOH358
A	HOH361

---

site_id	AC8
Number of Residues	10
Details	binding site for residue GOL A 208

Chain	Residue
A	ARG103
A	ARG103
A	ARG104
A	VAL126
A	HIS127
A	ARG128
A	SO4205
A	SO4205
A	SO4206
A	HOH309

---

site_id	AC9
Number of Residues	4
Details	binding site for residue GOL A 209

Chain	Residue
A	SER47
A	LYS54
A	HOH332
A	HOH348

---

site_id	AD1
Number of Residues	8
Details	binding site for residue GOL A 210

Chain	Residue
A	LYS14
A	ASN15
A	ALA18
A	ASP26
A	GLY28
A	VAL75
A	ASP97
A	ILE98

---

site_id	AD2
Number of Residues	3
Details	binding site for residue GOL A 211

Chain	Residue
A	ARG50
A	MET73
A	HOH313

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Motif: {"description":"Gate loop","evidences":[{"source":"UniProtKB","id":"Q8VZS8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Motif: {"description":"Latch loop","evidences":[{"source":"UniProtKB","id":"Q8VZS8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	13
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19898494","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19933100","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Involved in interactions with PP2Cs","evidences":[{"source":"PubMed","id":"19407142","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by CARK1","evidences":[{"source":"PubMed","id":"29928509","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---