5UR2
Crystal structure of proline utilization A (PutA) from Bdellovibrio bacteriovorus inactivated by N-propargylglycine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0003842 | molecular_function | L-glutamate gamma-semialdehyde dehydrogenase activity |
| A | 0004657 | molecular_function | proline dehydrogenase activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0006562 | biological_process | L-proline catabolic process |
| A | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| A | 0010133 | biological_process | obsolete L-proline catabolic process to L-glutamate |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0003842 | molecular_function | L-glutamate gamma-semialdehyde dehydrogenase activity |
| B | 0004657 | molecular_function | proline dehydrogenase activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0006562 | biological_process | L-proline catabolic process |
| B | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| B | 0010133 | biological_process | obsolete L-proline catabolic process to L-glutamate |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0003842 | molecular_function | L-glutamate gamma-semialdehyde dehydrogenase activity |
| C | 0004657 | molecular_function | proline dehydrogenase activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0006562 | biological_process | L-proline catabolic process |
| C | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| C | 0010133 | biological_process | obsolete L-proline catabolic process to L-glutamate |
| C | 0016491 | molecular_function | oxidoreductase activity |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0003842 | molecular_function | L-glutamate gamma-semialdehyde dehydrogenase activity |
| D | 0004657 | molecular_function | proline dehydrogenase activity |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0006562 | biological_process | L-proline catabolic process |
| D | 0009898 | cellular_component | cytoplasmic side of plasma membrane |
| D | 0010133 | biological_process | obsolete L-proline catabolic process to L-glutamate |
| D | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | binding site for residue P5F A 1001 |
| Chain | Residue |
| A | LYS196 |
| A | GLY302 |
| A | ALA303 |
| A | TRP305 |
| A | TYR322 |
| A | THR323 |
| A | ASN324 |
| A | LYS325 |
| A | SER328 |
| A | ALA351 |
| A | SER352 |
| A | ASP237 |
| A | HIS353 |
| A | ASN354 |
| A | GLN378 |
| A | MET379 |
| A | LEU380 |
| A | TYR401 |
| A | GLU420 |
| A | GLU425 |
| A | TRP427 |
| A | HOH1302 |
| A | MET238 |
| A | HOH1309 |
| A | HOH1341 |
| A | VAL269 |
| A | GLN271 |
| A | TYR273 |
| A | ARG298 |
| A | VAL300 |
| A | LYS301 |
| site_id | AC2 |
| Number of Residues | 34 |
| Details | binding site for Di-peptide P5F B 1001 and LYS B 196 |
| Chain | Residue |
| B | TYR156 |
| B | VAL195 |
| B | MET197 |
| B | THR198 |
| B | ALA199 |
| B | ASP237 |
| B | MET238 |
| B | VAL269 |
| B | GLN271 |
| B | TYR273 |
| B | ARG298 |
| B | VAL300 |
| B | LYS301 |
| B | GLY302 |
| B | ALA303 |
| B | TRP305 |
| B | TYR322 |
| B | THR323 |
| B | ASN324 |
| B | LYS325 |
| B | SER328 |
| B | ALA351 |
| B | SER352 |
| B | HIS353 |
| B | ASN354 |
| B | GLN378 |
| B | MET379 |
| B | LEU380 |
| B | TYR401 |
| B | GLU420 |
| B | GLU425 |
| B | SER426 |
| B | TRP427 |
| B | HOH1220 |
| site_id | AC3 |
| Number of Residues | 33 |
| Details | binding site for Di-peptide P5F C 1001 and LYS C 196 |
| Chain | Residue |
| C | TYR156 |
| C | VAL195 |
| C | MET197 |
| C | THR198 |
| C | ALA199 |
| C | ASP237 |
| C | MET238 |
| C | GLU239 |
| C | VAL269 |
| C | GLN271 |
| C | TYR273 |
| C | VAL300 |
| C | LYS301 |
| C | GLY302 |
| C | ALA303 |
| C | TYR304 |
| C | TRP305 |
| C | TYR322 |
| C | THR323 |
| C | ASN324 |
| C | LYS325 |
| C | SER328 |
| C | SER352 |
| C | HIS353 |
| C | ASN354 |
| C | GLN378 |
| C | MET379 |
| C | LEU380 |
| C | TYR401 |
| C | GLU420 |
| C | GLU425 |
| C | TRP427 |
| C | HOH1257 |
| site_id | AC4 |
| Number of Residues | 34 |
| Details | binding site for Di-peptide P5F D 1001 and LYS D 196 |
| Chain | Residue |
| D | VAL195 |
| D | MET197 |
| D | THR198 |
| D | ALA199 |
| D | ASP237 |
| D | MET238 |
| D | GLU239 |
| D | VAL269 |
| D | GLN271 |
| D | TYR273 |
| D | VAL300 |
| D | LYS301 |
| D | GLY302 |
| D | ALA303 |
| D | TYR304 |
| D | TRP305 |
| D | TYR322 |
| D | THR323 |
| D | ASN324 |
| D | LYS325 |
| D | SER328 |
| D | SER352 |
| D | HIS353 |
| D | ASN354 |
| D | GLN378 |
| D | MET379 |
| D | LEU380 |
| D | TYR401 |
| D | GLU420 |
| D | SER426 |
| D | TRP427 |
| D | HOH1117 |
| D | HOH1220 |
| D | TYR156 |
Functional Information from PROSITE/UniProt
| site_id | PS00070 |
| Number of Residues | 12 |
| Details | ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. FgFSGQKCSAAS |
| Chain | Residue | Details |
| A | PHE771-SER782 |
| site_id | PS00687 |
| Number of Residues | 8 |
| Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. IEMGGKNA |
| Chain | Residue | Details |
| A | ILE743-ALA750 |
