5UQT

Clostridium difficile Toxin B (TcdB) glucosyltransferase domain co-crystallized with apigenin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016757	molecular_function	glycosyltransferase activity
B	0016757	molecular_function	glycosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue MN A 601

Chain	Residue
A	ASP288
A	GLU515
A	SER518

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site_id	AC2
Number of Residues	3
Details	binding site for residue MN B 601

Chain	Residue
B	ASP288
B	GLU515
B	SER518

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site_id	AC3
Number of Residues	10
Details	binding site for residue AGI B 602

Chain	Residue
A	MET448
B	ALA439
B	ASN440
B	ALA441
B	GLY444
B	ARG445
B	MET448
A	ASN440
A	GLY444
A	ARG445

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	744
Details	Domain: {"description":"GT44","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	178
Details	Region: {"description":"Four-helical bundle","evidences":[{"source":"PubMed","id":"25882477","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	744
Details	Region: {"description":"Glucosyltransferase region","evidences":[{"source":"PubMed","id":"29146177","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16054646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31308519","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OQ7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16054646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31308519","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6OQ5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16054646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31308519","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2BVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OQ7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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