5UQQ

Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0005975	biological_process	carbohydrate metabolic process
A	0006099	biological_process	tricarboxylic acid cycle
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0019543	biological_process	propionate catabolic process
A	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
A	0036440	molecular_function	citrate synthase activity
A	0046912	molecular_function	acyltransferase activity, acyl groups converted into alkyl on transfer
A	0050440	molecular_function	2-methylcitrate synthase activity
B	0005739	cellular_component	mitochondrion
B	0005759	cellular_component	mitochondrial matrix
B	0005975	biological_process	carbohydrate metabolic process
B	0006099	biological_process	tricarboxylic acid cycle
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0019543	biological_process	propionate catabolic process
B	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
B	0036440	molecular_function	citrate synthase activity
B	0046912	molecular_function	acyltransferase activity, acyl groups converted into alkyl on transfer
B	0050440	molecular_function	2-methylcitrate synthase activity
C	0005739	cellular_component	mitochondrion
C	0005759	cellular_component	mitochondrial matrix
C	0005975	biological_process	carbohydrate metabolic process
C	0006099	biological_process	tricarboxylic acid cycle
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0019543	biological_process	propionate catabolic process
C	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
C	0036440	molecular_function	citrate synthase activity
C	0046912	molecular_function	acyltransferase activity, acyl groups converted into alkyl on transfer
C	0050440	molecular_function	2-methylcitrate synthase activity
D	0005739	cellular_component	mitochondrion
D	0005759	cellular_component	mitochondrial matrix
D	0005975	biological_process	carbohydrate metabolic process
D	0006099	biological_process	tricarboxylic acid cycle
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0019543	biological_process	propionate catabolic process
D	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
D	0036440	molecular_function	citrate synthase activity
D	0046912	molecular_function	acyltransferase activity, acyl groups converted into alkyl on transfer
D	0050440	molecular_function	2-methylcitrate synthase activity
E	0005739	cellular_component	mitochondrion
E	0005759	cellular_component	mitochondrial matrix
E	0005975	biological_process	carbohydrate metabolic process
E	0006099	biological_process	tricarboxylic acid cycle
E	0016740	molecular_function	transferase activity
E	0016746	molecular_function	acyltransferase activity
E	0019543	biological_process	propionate catabolic process
E	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
E	0036440	molecular_function	citrate synthase activity
E	0046912	molecular_function	acyltransferase activity, acyl groups converted into alkyl on transfer
E	0050440	molecular_function	2-methylcitrate synthase activity
F	0005739	cellular_component	mitochondrion
F	0005759	cellular_component	mitochondrial matrix
F	0005975	biological_process	carbohydrate metabolic process
F	0006099	biological_process	tricarboxylic acid cycle
F	0016740	molecular_function	transferase activity
F	0016746	molecular_function	acyltransferase activity
F	0019543	biological_process	propionate catabolic process
F	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
F	0036440	molecular_function	citrate synthase activity
F	0046912	molecular_function	acyltransferase activity, acyl groups converted into alkyl on transfer
F	0050440	molecular_function	2-methylcitrate synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue SRT B 501

Chain	Residue
B	ARG74
C	HOH561
B	HIS351
B	GLY352
B	VAL353
B	HOH616
B	HOH644
B	HOH837
C	ARG454
C	LYS456

---

Functional Information from PROSITE/UniProt

site_id	PS00480
Number of Residues	13
Details	CITRATE_SYNTHASE Citrate synthase signature. GYGHgVl.RkpDPR

Chain	Residue	Details
B	GLY348-ARG360

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"O34002","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	54
Details	Binding site: {"description":"in chain B","evidences":[{"source":"UniProtKB","id":"B0YD89","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	30
Details	Binding site: {"description":"in chain A","evidences":[{"source":"UniProtKB","id":"B0YD89","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---