5UQN
Clostridium difficile Toxin B (TcdB) glucosyltransferase domain in complex with U2F
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 601 |
| Chain | Residue |
| A | ASP288 |
| A | GLU515 |
| A | U2F602 |
| A | HOH750 |
| A | HOH806 |
| site_id | AC2 |
| Number of Residues | 29 |
| Details | binding site for residue U2F A 602 |
| Chain | Residue |
| A | LEU265 |
| A | ALA266 |
| A | SER269 |
| A | ASP270 |
| A | ARG273 |
| A | TYR284 |
| A | ASP286 |
| A | VAL287 |
| A | ASP288 |
| A | ILE383 |
| A | ASN384 |
| A | GLN385 |
| A | THR465 |
| A | ILE466 |
| A | GLY470 |
| A | PRO471 |
| A | SER518 |
| A | LEU519 |
| A | TRP520 |
| A | MN601 |
| A | HOH719 |
| A | HOH744 |
| A | HOH750 |
| A | HOH759 |
| A | HOH806 |
| A | VAL101 |
| A | TRP102 |
| A | ILE103 |
| A | ASN139 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 603 |
| Chain | Residue |
| A | MET516 |
| A | SER518 |
| A | SER521 |
| A | PHE522 |
| A | ASP523 |
| A | ARG526 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 604 |
| Chain | Residue |
| A | ARG526 |
| A | GLN530 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 372 |
| Details | Domain: {"description":"GT44","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 89 |
| Details | Region: {"description":"Four-helical bundle","evidences":[{"source":"PubMed","id":"25882477","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 372 |
| Details | Region: {"description":"Glucosyltransferase region","evidences":[{"source":"PubMed","id":"29146177","evidenceCode":"ECO:0000303"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16054646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31308519","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OQ7","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16054646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31308519","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6OQ5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16054646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31308519","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2BVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OQ7","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
