5UQL
Clostridium difficile toxin A (TcdA) glucosyltransferase domain in complex with U2F
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue MN A 601 |
Chain | Residue |
A | ASP287 |
A | GLU514 |
A | U2F602 |
A | HOH711 |
A | HOH795 |
site_id | AC2 |
Number of Residues | 27 |
Details | binding site for residue U2F A 602 |
Chain | Residue |
A | LEU264 |
A | ALA265 |
A | SER268 |
A | ASP269 |
A | ARG272 |
A | TYR283 |
A | ASP285 |
A | VAL286 |
A | ASP287 |
A | ILE382 |
A | ASN383 |
A | GLN384 |
A | GLY469 |
A | GLU514 |
A | SER517 |
A | LEU518 |
A | TRP519 |
A | MN601 |
A | HOH803 |
A | HOH830 |
A | HOH884 |
A | HOH887 |
A | HOH948 |
A | VAL100 |
A | TRP101 |
A | ILE102 |
A | ASN138 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22267739, ECO:0000269|PubMed:22747490, ECO:0000269|PubMed:28433497, ECO:0007744|PDB:3SRZ, ECO:0007744|PDB:4DMV, ECO:0007744|PDB:5UQK, ECO:0007744|PDB:5UQL |
Chain | Residue | Details |
A | VAL100 | |
A | SER268 | |
A | SER517 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22267739, ECO:0000269|PubMed:28433497, ECO:0007744|PDB:3SRZ, ECO:0007744|PDB:5UQK, ECO:0007744|PDB:5UQL |
Chain | Residue | Details |
A | ASN138 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22267739, ECO:0007744|PDB:3SS1 |
Chain | Residue | Details |
A | ASP285 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22267739, ECO:0000269|PubMed:22747490, ECO:0000269|PubMed:28433497, ECO:0007744|PDB:3SRZ, ECO:0007744|PDB:3SS1, ECO:0007744|PDB:5UQK, ECO:0007744|PDB:5UQL |
Chain | Residue | Details |
A | ASP287 | |
A | GLU514 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:27571750, ECO:0007744|PDB:4R04 |
Chain | Residue | Details |
A | GLU544 |
site_id | SWS_FT_FI6 |
Number of Residues | 1 |
Details | SITE: Cleavage; by autolysis => ECO:0000305|PubMed:19553670 |
Chain | Residue | Details |
A | LEU542 |