5UQK
Clostridium difficile toxin A (TcdA) glucosyltransferase domain in complex with U2F
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue U2F A 601 |
| Chain | Residue |
| A | VAL100 |
| A | TYR283 |
| A | ASP285 |
| A | VAL286 |
| A | ASP287 |
| A | ASN383 |
| A | GLN384 |
| A | THR464 |
| A | SER517 |
| A | MN602 |
| A | HOH710 |
| A | TRP101 |
| A | HOH722 |
| A | HOH899 |
| A | HOH909 |
| A | ILE102 |
| A | ASN138 |
| A | LEU264 |
| A | ALA265 |
| A | SER268 |
| A | ASP269 |
| A | ARG272 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue MN A 602 |
| Chain | Residue |
| A | ASP287 |
| A | GLU514 |
| A | SER517 |
| A | U2F601 |
| A | HOH705 |
| A | HOH710 |
| A | HOH765 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 372 |
| Details | Domain: {"description":"GT44","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 372 |
| Details | Region: {"description":"Glucosyltransferase region","evidences":[{"source":"PubMed","id":"29146177","evidenceCode":"ECO:0000303"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22267739","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22747490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3SRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DMV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22267739","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3SRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22267739","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3SS1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22267739","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22747490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28433497","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3SRZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SS1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UQL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
