Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue 8HD A 201 |
| Chain | Residue |
| A | ARG8 |
| A | GLY49 |
| A | VAL82 |
| A | ILE84 |
| A | HOH302 |
| A | HOH333 |
| A | HOH348 |
| A | HOH375 |
| B | ASP25 |
| B | GLY27 |
| B | ASP29 |
| A | LEU23 |
| B | ASP30 |
| B | GLY48 |
| B | GLY49 |
| B | ILE50 |
| B | ILE84 |
| B | HOH251 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | VAL32 |
| A | GLY48 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 202 |
| Chain | Residue |
| A | ASP60 |
| A | HOH322 |
| A | HOH355 |
| A | HOH371 |
| A | HOH373 |
| A | HOH395 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 203 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| A | HOH324 |
| A | HOH417 |
| B | ARG41 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 204 |
| Chain | Residue |
| A | LYS45 |
| A | MET46 |
| A | HOH317 |
| A | HOH329 |
| B | GLN92 |
| B | CL103 |
| B | HOH237 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 101 |
| Chain | Residue |
| B | ASP60 |
| B | HOH217 |
| B | HOH224 |
| B | HOH281 |
| B | HOH313 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 102 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 103 |
| Chain | Residue |
| A | GOL204 |
| B | THR74 |
| B | ASN88 |
| B | HOH231 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 104 |
| Chain | Residue |
| A | LEU5 |
| A | HOH319 |
| A | HOH328 |
| B | THR91 |
| B | ALA95 |
| B | HOH247 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
