5UNM
LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, substrate free form with flexible loop
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006163 | biological_process | purine nucleotide metabolic process |
| A | 0016783 | molecular_function | sulfurtransferase activity |
| A | 0016829 | molecular_function | lyase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006163 | biological_process | purine nucleotide metabolic process |
| B | 0016783 | molecular_function | sulfurtransferase activity |
| B | 0016829 | molecular_function | lyase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006163 | biological_process | purine nucleotide metabolic process |
| C | 0016783 | molecular_function | sulfurtransferase activity |
| C | 0016829 | molecular_function | lyase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006163 | biological_process | purine nucleotide metabolic process |
| D | 0016783 | molecular_function | sulfurtransferase activity |
| D | 0016829 | molecular_function | lyase activity |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0005524 | molecular_function | ATP binding |
| E | 0006163 | biological_process | purine nucleotide metabolic process |
| E | 0016783 | molecular_function | sulfurtransferase activity |
| E | 0016829 | molecular_function | lyase activity |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0005524 | molecular_function | ATP binding |
| F | 0006163 | biological_process | purine nucleotide metabolic process |
| F | 0016783 | molecular_function | sulfurtransferase activity |
| F | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 A 301 |
| Chain | Residue |
| A | CYS176 |
| A | SER180 |
| A | ARG181 |
| A | ARG212 |
| A | ARG214 |
| A | PHE258 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 B 301 |
| Chain | Residue |
| B | ARG212 |
| B | ARG214 |
| B | PHE258 |
| B | PRO134 |
| B | CYS176 |
| B | SER180 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 C 301 |
| Chain | Residue |
| C | CYS176 |
| C | SER180 |
| C | ARG212 |
| C | ARG214 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 D 301 |
| Chain | Residue |
| D | CYS176 |
| D | SER180 |
| D | ARG212 |
| D | ARG214 |
| D | PHE258 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 E 301 |
| Chain | Residue |
| E | CYS176 |
| E | SER180 |
| E | ARG212 |
| E | ARG214 |
| E | HOH411 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 F 301 |
| Chain | Residue |
| F | CYS176 |
| F | SER180 |
| F | ARG212 |
| F | ARG214 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Nucleophile and sulfur donor","evidences":[{"source":"PubMed","id":"27114550","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"2,3-didehydroalanine (Cys)","evidences":[{"source":"PubMed","id":"27114550","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
