5UM1
XFEL structure of influenza A M2 wild type TM domain at intermediate pH in the lipidic cubic phase at room temperature
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 101 |
| Chain | Residue |
| A | SER22 |
| A | SER22 |
| A | SER22 |
| A | HOH201 |
| A | HOH201 |
| A | HOH201 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 102 |
| Chain | Residue |
| A | SER23 |
| A | SER23 |
| A | SER23 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CA A 103 |
| Chain | Residue |
| A | ASP24 |
| A | HOH203 |
| A | HOH204 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Signal-anchor for type III membrane protein","evidences":[{"source":"HAMAP-Rule","id":"MF_04069","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Essential for channel activity, possibly by being protonated during channel activation, and by forming the channel gate and the selective filter","evidences":[{"source":"HAMAP-Rule","id":"MF_04069","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Seems to be involved in pH gating","evidences":[{"source":"HAMAP-Rule","id":"MF_04069","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04069","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
