Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5ULJ

Crystal structure of Scheffersomyces stipitis Rai1 in complex with (3'-NADP)+ and calcium ion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A	0000956	biological_process	nuclear-transcribed mRNA catabolic process
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0005634	cellular_component	nucleus
A	0005829	cellular_component	cytosol
A	0006397	biological_process	mRNA processing
A	0016787	molecular_function	hydrolase activity
A	0030234	molecular_function	enzyme regulator activity
A	0030846	biological_process	termination of RNA polymerase II transcription, poly(A)-coupled
A	0031087	biological_process	deadenylation-independent decapping of nuclear-transcribed mRNA
A	0034353	molecular_function	mRNA 5'-diphosphatase activity
A	0046872	molecular_function	metal ion binding
A	0071035	biological_process	nuclear polyadenylation-dependent rRNA catabolic process
A	0110155	biological_process	NAD-cap decapping
A	1904595	biological_process	positive regulation of termination of RNA polymerase II transcription
A	1990174	molecular_function	phosphodiesterase decapping endonuclease activity
B	0000166	molecular_function	nucleotide binding
B	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B	0000956	biological_process	nuclear-transcribed mRNA catabolic process
B	0003723	molecular_function	RNA binding
B	0004518	molecular_function	nuclease activity
B	0005634	cellular_component	nucleus
B	0005829	cellular_component	cytosol
B	0006397	biological_process	mRNA processing
B	0016787	molecular_function	hydrolase activity
B	0030234	molecular_function	enzyme regulator activity
B	0030846	biological_process	termination of RNA polymerase II transcription, poly(A)-coupled
B	0031087	biological_process	deadenylation-independent decapping of nuclear-transcribed mRNA
B	0034353	molecular_function	mRNA 5'-diphosphatase activity
B	0046872	molecular_function	metal ion binding
B	0071035	biological_process	nuclear polyadenylation-dependent rRNA catabolic process
B	0110155	biological_process	NAD-cap decapping
B	1904595	biological_process	positive regulation of termination of RNA polymerase II transcription
B	1990174	molecular_function	phosphodiesterase decapping endonuclease activity
C	0000166	molecular_function	nucleotide binding
C	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C	0000956	biological_process	nuclear-transcribed mRNA catabolic process
C	0003723	molecular_function	RNA binding
C	0004518	molecular_function	nuclease activity
C	0005634	cellular_component	nucleus
C	0005829	cellular_component	cytosol
C	0006397	biological_process	mRNA processing
C	0016787	molecular_function	hydrolase activity
C	0030234	molecular_function	enzyme regulator activity
C	0030846	biological_process	termination of RNA polymerase II transcription, poly(A)-coupled
C	0031087	biological_process	deadenylation-independent decapping of nuclear-transcribed mRNA
C	0034353	molecular_function	mRNA 5'-diphosphatase activity
C	0046872	molecular_function	metal ion binding
C	0071035	biological_process	nuclear polyadenylation-dependent rRNA catabolic process
C	0110155	biological_process	NAD-cap decapping
C	1904595	biological_process	positive regulation of termination of RNA polymerase II transcription
C	1990174	molecular_function	phosphodiesterase decapping endonuclease activity
D	0000166	molecular_function	nucleotide binding
D	0000448	biological_process	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D	0000466	biological_process	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D	0000956	biological_process	nuclear-transcribed mRNA catabolic process
D	0003723	molecular_function	RNA binding
D	0004518	molecular_function	nuclease activity
D	0005634	cellular_component	nucleus
D	0005829	cellular_component	cytosol
D	0006397	biological_process	mRNA processing
D	0016787	molecular_function	hydrolase activity
D	0030234	molecular_function	enzyme regulator activity
D	0030846	biological_process	termination of RNA polymerase II transcription, poly(A)-coupled
D	0031087	biological_process	deadenylation-independent decapping of nuclear-transcribed mRNA
D	0034353	molecular_function	mRNA 5'-diphosphatase activity
D	0046872	molecular_function	metal ion binding
D	0071035	biological_process	nuclear polyadenylation-dependent rRNA catabolic process
D	0110155	biological_process	NAD-cap decapping
D	1904595	biological_process	positive regulation of termination of RNA polymerase II transcription
D	1990174	molecular_function	phosphodiesterase decapping endonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue CA A 401

Chain	Residue
A	GLU179
A	ASP230
A	GLU249
A	LEU250
A	0WD402
A	HOH504
A	HOH505
A	HOH512

site_id	AC2
Number of Residues	16
Details	binding site for residue 0WD A 402

Chain	Residue
A	MET77
A	TYR107
A	ARG108
A	GLY109
A	TYR176
A	GLN209
A	ALA226
A	GLY227
A	GLU228
A	LYS251
A	GLN275
A	CA401
A	HOH522
A	HOH543
A	HOH669
A	ASN76

site_id	AC3
Number of Residues	7
Details	binding site for residue CA B 401

Chain	Residue
B	ASP230
B	GLU249
B	LEU250
B	0WD402
B	HOH521
B	HOH540
B	HOH604

site_id	AC4
Number of Residues	29
Details	binding site for residue 0WD B 402

Chain	Residue
B	GLU73
B	ASN76
B	MET77
B	TYR107
B	ARG108
B	GLY109
B	SER140
B	GLU145
B	TYR176
B	ASN206
B	GLN209
B	GLY227
B	GLU228
B	GLU249
B	LYS251
B	CA401
B	HOH503
B	HOH506
B	HOH520
B	HOH521
B	HOH525
B	HOH551
B	HOH560
B	HOH601
B	HOH604
B	HOH617
B	HOH658
B	HOH689
B	HOH691

site_id	AC5
Number of Residues	5
Details	binding site for residue PPV C 401

Chain	Residue
C	ARG108
C	GLY109
C	GLY227
C	GLU228
C	HOH513

site_id	AC6
Number of Residues	8
Details	binding site for residue PPV D 401

Chain	Residue
D	TYR107
D	ARG108
D	GLY109
D	ALA226
D	GLY227
D	GLU228
D	GLN275
D	HOH517

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28283058","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5ULJ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)