Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SF4 A 801 |
| Chain | Residue |
| A | CYS313 |
| A | SER316 |
| A | CYS318 |
| A | CYS321 |
| A | ARG399 |
| A | DTT803 |
| site_id | AC2 |
| Number of Residues | 42 |
| Details | binding site for residue B12 A 802 |
| Chain | Residue |
| A | GLN161 |
| A | GLY182 |
| A | LEU183 |
| A | SER184 |
| A | PHE187 |
| A | GLY216 |
| A | ASN217 |
| A | CYS237 |
| A | LYS239 |
| A | GLU240 |
| A | GLY241 |
| A | GLU242 |
| A | GLU308 |
| A | ARG311 |
| A | CYS321 |
| A | PRO322 |
| A | HIS325 |
| A | LYS326 |
| A | ALA361 |
| A | GLU363 |
| A | GLU545 |
| A | DTT803 |
| A | EDO821 |
| A | HOH904 |
| A | HOH924 |
| A | HOH987 |
| A | HOH1001 |
| A | HOH1009 |
| A | HOH1032 |
| A | HOH1036 |
| A | HOH1064 |
| A | HOH1088 |
| A | HOH1142 |
| A | HOH1226 |
| A | HOH1267 |
| A | HOH1326 |
| A | HOH1331 |
| A | HOH1396 |
| A | HOH1420 |
| A | PHE131 |
| A | ARG135 |
| A | SER139 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue DTT A 803 |
| Chain | Residue |
| A | GLU363 |
| A | ALA397 |
| A | SF4801 |
| A | B12802 |
| A | HOH1031 |
| A | HOH1064 |
| A | HOH1126 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue MES A 804 |
| Chain | Residue |
| A | TRP88 |
| A | HIS89 |
| A | SER107 |
| A | CYS108 |
| A | ASP314 |
| A | ARG317 |
| A | GLU368 |
| A | PRO370 |
| A | HOH914 |
| A | HOH1321 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 805 |
| Chain | Residue |
| A | ASN468 |
| A | LEU469 |
| A | HOH948 |
| A | HOH1181 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 806 |
| Chain | Residue |
| A | LEU469 |
| A | ARG470 |
| A | VAL537 |
| A | HOH942 |
| A | HOH969 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 807 |
| Chain | Residue |
| A | MET475 |
| A | LEU493 |
| A | TYR534 |
| A | MET540 |
| A | LEU541 |
| A | HIS638 |
| A | HOH1055 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 808 |
| Chain | Residue |
| A | TYR539 |
| A | MET540 |
| A | ILE601 |
| A | EDO828 |
| A | HOH1078 |
| A | HOH1191 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 809 |
| Chain | Residue |
| A | VAL617 |
| A | THR714 |
| A | ASP715 |
| A | HOH1034 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 810 |
| Chain | Residue |
| A | ASP703 |
| A | ALA706 |
| A | ASP707 |
| A | LYS710 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 811 |
| Chain | Residue |
| A | HOH922 |
| A | HOH1204 |
| A | LYS257 |
| A | LEU258 |
| A | ASP259 |
| A | GLU269 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 812 |
| Chain | Residue |
| A | ASP259 |
| A | ASN276 |
| A | HOH1253 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 813 |
| Chain | Residue |
| A | GLU150 |
| A | HOH1344 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 814 |
| Chain | Residue |
| A | PRO75 |
| A | HOH1063 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 815 |
| Chain | Residue |
| A | THR373 |
| A | GLN376 |
| A | ARG377 |
| A | ASP380 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 816 |
| Chain | Residue |
| A | SER6 |
| A | SER9 |
| A | GLU44 |
| A | LYS588 |
| A | THR589 |
| A | GLY681 |
| A | HOH1358 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 817 |
| Chain | Residue |
| A | MET251 |
| A | ASN619 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 818 |
| Chain | Residue |
| A | LEU327 |
| A | ARG328 |
| A | SER329 |
| A | HOH932 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 819 |
| Chain | Residue |
| A | TYR627 |
| A | ARG634 |
| A | HOH1046 |
| A | HOH1163 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 820 |
| Chain | Residue |
| A | TYR201 |
| A | ARG230 |
| A | TYR231 |
| A | PRO232 |
| A | SER233 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 821 |
| Chain | Residue |
| A | ARG135 |
| A | TYR359 |
| A | B12802 |
| A | HOH1058 |
| A | HOH1170 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 822 |
| Chain | Residue |
| A | ILE24 |
| A | ASP344 |
| A | ARG347 |
| A | HOH901 |
| A | HOH1167 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 823 |
| Chain | Residue |
| A | PHE432 |
| A | GLU436 |
| A | GLY472 |
| A | HOH1126 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 824 |
| Chain | Residue |
| A | GLU545 |
| A | HOH924 |
| A | HOH1061 |
| A | HOH1382 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 825 |
| Chain | Residue |
| A | GLU94 |
| A | ILE95 |
| A | GLU96 |
| A | LYS239 |
| A | ASP324 |
| A | EDO826 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 826 |
| Chain | Residue |
| A | SER221 |
| A | PHE222 |
| A | ASP238 |
| A | ASP324 |
| A | EDO825 |
| A | HOH977 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 827 |
| Chain | Residue |
| A | HIS665 |
| A | LYS699 |
| A | LEU700 |
| A | ASP703 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 828 |
| Chain | Residue |
| A | SER538 |
| A | MET540 |
| A | ARG634 |
| A | EDO808 |
| A | HOH1078 |
| A | HOH1176 |
