5UJW

Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004807	molecular_function	triose-phosphate isomerase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006094	biological_process	gluconeogenesis
A	0006096	biological_process	glycolytic process
A	0016853	molecular_function	isomerase activity
A	0019563	biological_process	glycerol catabolic process
A	0046166	biological_process	glyceraldehyde-3-phosphate biosynthetic process
B	0004807	molecular_function	triose-phosphate isomerase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006094	biological_process	gluconeogenesis
B	0006096	biological_process	glycolytic process
B	0016853	molecular_function	isomerase activity
B	0019563	biological_process	glycerol catabolic process
B	0046166	biological_process	glyceraldehyde-3-phosphate biosynthetic process
C	0004807	molecular_function	triose-phosphate isomerase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006094	biological_process	gluconeogenesis
C	0006096	biological_process	glycolytic process
C	0016853	molecular_function	isomerase activity
C	0019563	biological_process	glycerol catabolic process
C	0046166	biological_process	glyceraldehyde-3-phosphate biosynthetic process
D	0004807	molecular_function	triose-phosphate isomerase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006094	biological_process	gluconeogenesis
D	0006096	biological_process	glycolytic process
D	0016853	molecular_function	isomerase activity
D	0019563	biological_process	glycerol catabolic process
D	0046166	biological_process	glyceraldehyde-3-phosphate biosynthetic process
E	0004807	molecular_function	triose-phosphate isomerase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006094	biological_process	gluconeogenesis
E	0006096	biological_process	glycolytic process
E	0016853	molecular_function	isomerase activity
E	0019563	biological_process	glycerol catabolic process
E	0046166	biological_process	glyceraldehyde-3-phosphate biosynthetic process
F	0004807	molecular_function	triose-phosphate isomerase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006094	biological_process	gluconeogenesis
F	0006096	biological_process	glycolytic process
F	0016853	molecular_function	isomerase activity
F	0019563	biological_process	glycerol catabolic process
F	0046166	biological_process	glyceraldehyde-3-phosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue 13P A 301

Chain	Residue
A	GLY209
A	GLY231
A	GLY232
A	IPA302
A	HOH408

---

site_id	AC2
Number of Residues	1
Details	binding site for residue IPA A 302

Chain	Residue
A	13P301

---

site_id	AC3
Number of Residues	3
Details	binding site for residue 13P C 301

Chain	Residue
C	GLY171
C	GLY232
C	IPA302

---

site_id	AC4
Number of Residues	1
Details	binding site for residue IPA C 302

Chain	Residue
C	13P301

---

site_id	AC5
Number of Residues	4
Details	binding site for residue EDO C 303

Chain	Residue
C	GLN2
C	LYS3
C	ILE250
C	HOH404

---

site_id	AC6
Number of Residues	9
Details	binding site for residue CIT D 301

Chain	Residue
D	LYS10
D	ILE170
D	GLY209
D	SER210
D	LYS212
D	GLY231
D	GLY232
D	HOH403
D	HOH407

---

Functional Information from PROSITE/UniProt

site_id	PS00171
Number of Residues	11
Details	TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG

Chain	Residue	Details
A	ALA163-GLY173

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Electrophile => ECO:0000255|HAMAP-Rule:MF_00147

Chain	Residue	Details
A	HIS93
B	HIS93
C	HIS93
D	HIS93
E	HIS93
F	HIS93

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00147

Chain	Residue	Details
A	GLU165
B	GLU165
C	GLU165
D	GLU165
E	GLU165
F	GLU165

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00147

Chain	Residue	Details
A	ASN8
C	GLY171
C	SER210
C	GLY231
D	ASN8
D	GLY171
D	SER210
D	GLY231
E	ASN8
E	GLY171
E	SER210
A	GLY171
E	GLY231
F	ASN8
F	GLY171
F	SER210
F	GLY231
A	SER210
A	GLY231
B	ASN8
B	GLY171
B	SER210
B	GLY231
C	ASN8

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