5UE8

The crystal structure of Munc13-1 C1C2BMUN domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005543	molecular_function	phospholipid binding
A	0007268	biological_process	chemical synaptic transmission
A	0019992	molecular_function	diacylglycerol binding
B	0005509	molecular_function	calcium ion binding
B	0005543	molecular_function	phospholipid binding
B	0007268	biological_process	chemical synaptic transmission
B	0019992	molecular_function	diacylglycerol binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1701

Chain	Residue
A	CYS580
A	CYS583
A	HIS605
A	CYS608

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 1702

Chain	Residue
A	HIS567
A	CYS597
A	CYS600
A	CYS616

---

site_id	AC3
Number of Residues	2
Details	binding site for residue CL A 1703

Chain	Residue
A	GLU837
A	ASN542

---

site_id	AC4
Number of Residues	1
Details	binding site for residue CL B 1601

Chain	Residue
B	GLU837

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN B 1602

Chain	Residue
B	CYS580
B	CYS583
B	HIS605
B	CYS608

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN B 1603

Chain	Residue
B	HIS567
B	CYS597
B	CYS600
B	CYS616

---

Functional Information from PROSITE/UniProt

site_id	PS00479
Number of Residues	50
Details	ZF_DAG_PE_1 Zinc finger phorbol-ester/DAG-type signature. HnFevwtattpty.CyeCeglLwgiarqgmr.CteCgvkcHekCqdllnad..C

Chain	Residue	Details
A	HIS567-CYS616

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	100
Details	Zinc finger: {"description":"Phorbol-ester/DAG-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00226","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00041","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	143
Details	Domain: {"description":"MHD1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00587","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---