Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000226 | biological_process | microtubule cytoskeleton organization |
A | 0000278 | biological_process | mitotic cell cycle |
A | 0005200 | molecular_function | structural constituent of cytoskeleton |
A | 0005525 | molecular_function | GTP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005856 | cellular_component | cytoskeleton |
A | 0005874 | cellular_component | microtubule |
A | 0007017 | biological_process | microtubule-based process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0000226 | biological_process | microtubule cytoskeleton organization |
B | 0000278 | biological_process | mitotic cell cycle |
B | 0003924 | molecular_function | GTPase activity |
B | 0005200 | molecular_function | structural constituent of cytoskeleton |
B | 0005525 | molecular_function | GTP binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005856 | cellular_component | cytoskeleton |
B | 0005874 | cellular_component | microtubule |
B | 0007017 | biological_process | microtubule-based process |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 21 |
Details | binding site for residue GTP A 501 |
Chain | Residue |
A | GLY10 |
A | SER140 |
A | GLY142 |
A | GLY143 |
A | GLY144 |
A | THR145 |
A | GLY146 |
A | THR179 |
A | TYR224 |
A | LEU227 |
A | ASN228 |
A | GLN11 |
A | MG502 |
B | LYS252 |
A | GLY12 |
A | GLN15 |
A | ASP69 |
A | GLU71 |
A | ASP98 |
A | ALA99 |
A | ASN101 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue MG A 502 |
Chain | Residue |
A | ASP69 |
A | GLU71 |
A | ASP98 |
A | GTP501 |
site_id | AC3 |
Number of Residues | 13 |
Details | binding site for residue GDP B 501 |
Chain | Residue |
B | GLY10 |
B | GLN11 |
B | CYS12 |
B | GLN15 |
B | ASN99 |
B | SER138 |
B | GLY142 |
B | THR143 |
B | GLY144 |
B | VAL169 |
B | LEU207 |
B | TYR222 |
B | ASN226 |
Functional Information from PROSITE/UniProt
site_id | PS00227 |
Number of Residues | 7 |
Details | TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG |
Chain | Residue | Details |
B | GLY140-GLY146 | |
A | GLY142-GLY148 | |
site_id | PS00228 |
Number of Residues | 4 |
Details | TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI |
Chain | Residue | Details |
B | MET1-ILE4 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLU254 | |
B | SER138 | |
B | GLY142 | |
B | THR143 | |
B | GLY144 | |
B | ASN204 | |
B | ASN226 | |
Chain | Residue | Details |
A | GLN11 | |
A | GLU71 | |
A | SER140 | |
A | GLY144 | |
A | THR145 | |
A | THR179 | |
A | ASN206 | |
A | ASN228 | |
Chain | Residue | Details |
A | LYS40 | |