Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 501 |
| Chain | Residue |
| A | LYS359 |
| A | ARG386 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 502 |
| Chain | Residue |
| A | HIS208 |
| A | HIS264 |
| A | CYS266 |
| A | HIS278 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue PO4 A 503 |
| Chain | Residue |
| A | ARG204 |
| A | HIS208 |
| A | TYR246 |
| A | EDO509 |
| A | HOH707 |
| A | HOH770 |
| A | HOH847 |
| A | HIS123 |
| A | HIS143 |
| A | TYR188 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | ASN299 |
| A | GLU301 |
| A | LYS317 |
| A | TRP371 |
| A | EDO510 |
| A | HOH822 |
| A | HOH978 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue K A 505 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | THR280 |
| A | PHE329 |
| A | THR355 |
| A | LYS359 |
| A | HOH786 |
| A | HOH894 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | HIS208 |
| A | ARG209 |
| A | HOH626 |
| A | HOH667 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | ASP211 |
| A | LYS232 |
| A | HIS233 |
| A | HOH607 |
| A | HOH749 |
| B | GLY368 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | HIS143 |
| A | HIS158 |
| A | ARG204 |
| A | ALA207 |
| A | HIS208 |
| A | PO4503 |
| A | HOH862 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 510 |
| Chain | Residue |
| A | ASP315 |
| A | GLU316 |
| A | MET319 |
| A | ARG322 |
| A | GOL504 |
| B | ARG169 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 511 |
| Chain | Residue |
| A | TYR188 |
| A | TYR246 |
| A | ARG282 |
| A | PHE329 |
| A | HOH742 |
| A | HOH838 |
| A | HOH847 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 501 |
| Chain | Residue |
| B | LYS359 |
| B | ARG386 |
| B | HOH1049 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 502 |
| Chain | Residue |
| B | HIS208 |
| B | HIS264 |
| B | CYS266 |
| B | HIS278 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 B 503 |
| Chain | Residue |
| B | HIS123 |
| B | HIS143 |
| B | TYR188 |
| B | ARG204 |
| B | HIS208 |
| B | TYR246 |
| B | EDO505 |
| B | HOH686 |
| B | HOH692 |
| site_id | AD6 |
| Number of Residues | 1 |
| Details | binding site for residue K B 504 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | HIS143 |
| B | ARG204 |
| B | ALA207 |
| B | HIS208 |
| B | PO4503 |
| site_id | AD8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 506 |
| Chain | Residue |
| B | THR280 |
| B | THR328 |
| B | PHE329 |
| B | THR355 |
| B | LYS359 |
| B | HOH680 |
| B | HOH761 |
| B | HOH903 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 507 |
| Chain | Residue |
| B | ARG105 |
| B | GLY107 |
| B | HOH882 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS123 | |
| B | HIS123 | |
| Chain | Residue | Details |
| A | TYR188 | |
| B | TYR188 | |
| Chain | Residue | Details |
| A | CYS266 | |
| A | HIS278 | |
| B | ASN60 | |
| B | ASN122 | |
| B | LYS125 | |
| B | HIS143 | |
| B | ARG204 | |
| B | HIS208 | |
| B | TYR246 | |
| B | HIS264 | |
| B | CYS266 | |
| B | HIS278 | |
| A | ASN60 | |
| A | ASN122 | |
| A | LYS125 | |
| A | HIS143 | |
| A | ARG204 | |
| A | HIS208 | |
| A | TYR246 | |
| A | HIS264 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Neutralizes the sugar carboxylate group at subsite +1 => ECO:0000305|PubMed:28290654 |
| Chain | Residue | Details |
| A | ARG204 | |
| B | ARG204 | |
