5U95
Structure of the open conformation of 4-coumarate-CoA ligase from Nicotiana tabacum
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0009611 | biological_process | response to wounding |
| A | 0009698 | biological_process | phenylpropanoid metabolic process |
| A | 0009753 | biological_process | response to jasmonic acid |
| A | 0016207 | molecular_function | 4-coumarate-CoA ligase activity |
| A | 0016405 | molecular_function | CoA-ligase activity |
| A | 0016874 | molecular_function | ligase activity |
| A | 0050563 | molecular_function | trans-feruloyl-CoA synthase activity |
| A | 0106286 | molecular_function | (E)-caffeate-CoA ligase activity |
| A | 0106290 | molecular_function | trans-cinnamate-CoA ligase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0009611 | biological_process | response to wounding |
| B | 0009698 | biological_process | phenylpropanoid metabolic process |
| B | 0009753 | biological_process | response to jasmonic acid |
| B | 0016207 | molecular_function | 4-coumarate-CoA ligase activity |
| B | 0016405 | molecular_function | CoA-ligase activity |
| B | 0016874 | molecular_function | ligase activity |
| B | 0050563 | molecular_function | trans-feruloyl-CoA synthase activity |
| B | 0106286 | molecular_function | (E)-caffeate-CoA ligase activity |
| B | 0106290 | molecular_function | trans-cinnamate-CoA ligase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0009611 | biological_process | response to wounding |
| C | 0009698 | biological_process | phenylpropanoid metabolic process |
| C | 0009753 | biological_process | response to jasmonic acid |
| C | 0016207 | molecular_function | 4-coumarate-CoA ligase activity |
| C | 0016405 | molecular_function | CoA-ligase activity |
| C | 0016874 | molecular_function | ligase activity |
| C | 0050563 | molecular_function | trans-feruloyl-CoA synthase activity |
| C | 0106286 | molecular_function | (E)-caffeate-CoA ligase activity |
| C | 0106290 | molecular_function | trans-cinnamate-CoA ligase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0009611 | biological_process | response to wounding |
| D | 0009698 | biological_process | phenylpropanoid metabolic process |
| D | 0009753 | biological_process | response to jasmonic acid |
| D | 0016207 | molecular_function | 4-coumarate-CoA ligase activity |
| D | 0016405 | molecular_function | CoA-ligase activity |
| D | 0016874 | molecular_function | ligase activity |
| D | 0050563 | molecular_function | trans-feruloyl-CoA synthase activity |
| D | 0106286 | molecular_function | (E)-caffeate-CoA ligase activity |
| D | 0106290 | molecular_function | trans-cinnamate-CoA ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue CA A 601 |
| Chain | Residue |
| A | ILE178 |
| B | GLU268 |
| B | HOH731 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CA A 602 |
| Chain | Residue |
| A | ASN169 |
| D | ASP434 |
| D | LEU436 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CA B 601 |
| Chain | Residue |
| B | ASP434 |
| B | LEU436 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CA C 601 |
| Chain | Residue |
| C | LEU436 |
| C | ASP434 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CA D 601 |
| Chain | Residue |
| C | GLU268 |
| C | HOH758 |
| D | ILE178 |
| D | HOH815 |
Functional Information from PROSITE/UniProt
| site_id | PS00455 |
| Number of Residues | 12 |
| Details | AMP_BINDING Putative AMP-binding domain signature. LPYSSGTTGlPK |
| Chain | Residue | Details |
| A | LEU186-LYS197 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 276 |
| Details | Region: {"description":"SBD1","evidences":[{"source":"UniProtKB","id":"Q42524","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 268 |
| Details | Region: {"description":"SBD2","evidences":[{"source":"UniProtKB","id":"Q42524","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 41 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26412334","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5BSM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26412334","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5BSV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 19 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26412334","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5BSR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26412334","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
