Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0004402 | molecular_function | histone acetyltransferase activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1801 |
| Chain | Residue |
| A | CYS1200 |
| A | CYS1201 |
| A | HIS1292 |
| A | CYS1295 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1802 |
| Chain | Residue |
| A | CYS1284 |
| A | CYS1287 |
| A | CYS1309 |
| A | CYS1312 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1803 |
| Chain | Residue |
| A | CYS1711 |
| A | CYS1730 |
| A | CYS1733 |
| A | CYS1708 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1804 |
| Chain | Residue |
| A | CYS1721 |
| A | CYS1724 |
| A | HIS1739 |
| A | HIS1741 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1801 |
| Chain | Residue |
| B | CYS1200 |
| B | CYS1201 |
| B | HIS1292 |
| B | CYS1295 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1802 |
| Chain | Residue |
| B | CYS1284 |
| B | CYS1287 |
| B | CYS1309 |
| B | CYS1312 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1803 |
| Chain | Residue |
| B | CYS1708 |
| B | CYS1711 |
| B | CYS1730 |
| B | CYS1733 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1804 |
| Chain | Residue |
| B | CYS1721 |
| B | CYS1724 |
| B | HIS1739 |
| B | HIS1741 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY |
| Chain | Residue | Details |
| A | SER1109-TYR1168 | |
| site_id | PS01357 |
| Number of Residues | 26 |
| Details | ZF_ZZ_1 Zinc finger ZZ-type signature. CneCkhhvet..RWhCtv...CeDYdLCinC |
| Chain | Residue | Details |
| A | CYS1708-CYS1733 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 214 |
| Details | Domain: {"description":"Bromo","evidences":[{"source":"PROSITE-ProRule","id":"PRU00035","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 96 |
| Details | Zinc finger: {"description":"ZZ-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00228","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 92 |
| Details | Region: {"description":"Interaction with histone","evidences":[{"source":"UniProtKB","id":"Q92793","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 36 |
| Details | Region: {"description":"Interaction with ASF1A","evidences":[{"source":"UniProtKB","id":"Q92793","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Region: {"description":"Interaction with histone","evidences":[{"source":"UniProtKB","id":"Q09472","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q09472","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00228","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by IKKA","evidences":[{"source":"UniProtKB","id":"Q92793","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q92793","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]} |
