5U79
Crystal structure of a complex formed between MerB and Dimethyltin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016829 | molecular_function | lyase activity |
| A | 0018836 | molecular_function | alkylmercury lyase activity |
| A | 0046689 | biological_process | response to mercury ion |
| B | 0016829 | molecular_function | lyase activity |
| B | 0018836 | molecular_function | alkylmercury lyase activity |
| B | 0046689 | biological_process | response to mercury ion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN5 A 301 |
| Chain | Residue |
| A | ASP99 |
| A | HOH501 |
| A | HOH562 |
| A | HOH575 |
| A | HOH610 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue BR A 302 |
| Chain | Residue |
| A | LYS2 |
| B | PRO5 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 303 |
| Chain | Residue |
| A | HIS163 |
| A | TRP174 |
| A | HOH422 |
| A | HOH516 |
| B | HOH481 |
| A | CYS160 |
| A | HIS161 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue ZN5 B 301 |
| Chain | Residue |
| B | ASP99 |
| B | HOH424 |
| B | HOH590 |
| B | HOH602 |
| B | HOH621 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 302 |
| Chain | Residue |
| B | CYS160 |
| B | HIS161 |
| B | HIS163 |
| B | TRP174 |
| B | HIS178 |
| B | HOH477 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 297 |
| Chain | Residue | Details |
| A | CYS96 | activator, covalently attached, hydrogen bond donor, nucleophile, proton donor |
| A | ASP99 | activator, hydrogen bond acceptor, hydrogen bond donor, increase nucleophilicity, promote heterolysis, proton acceptor, proton donor |
| A | CYS159 | activator, covalently attached, nucleophile, proton donor |
| site_id | MCSA2 |
| Number of Residues | 3 |
| Details | M-CSA 297 |
| Chain | Residue | Details |
| B | CYS96 | activator, covalently attached, hydrogen bond donor, nucleophile, proton donor |
| B | ASP99 | activator, hydrogen bond acceptor, hydrogen bond donor, increase nucleophilicity, promote heterolysis, proton acceptor, proton donor |
| B | CYS159 | activator, covalently attached, nucleophile, proton donor |
