5U4T

Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0008168	molecular_function	methyltransferase activity
A	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0032259	biological_process	methylation
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue IOD A 402

Chain	Residue
A	ILE8

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site_id	AC2
Number of Residues	1
Details	binding site for residue IOD A 403

Chain	Residue
A	GLU11

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site_id	AC3
Number of Residues	2
Details	binding site for residue IOD A 404

Chain	Residue
A	ARG162
A	GLU177

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site_id	AC4
Number of Residues	3
Details	binding site for residue IOD A 405

Chain	Residue
A	ARG162
A	PHE175
A	HOH633

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site_id	AC5
Number of Residues	3
Details	binding site for residue IOD A 406

Chain	Residue
A	HOH586
A	LEU207
A	VAL291

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site_id	AC6
Number of Residues	1
Details	binding site for residue IOD A 408

Chain	Residue
A	PRO79

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site_id	AC7
Number of Residues	2
Details	binding site for residue IOD A 410

Chain	Residue
A	HIS86
A	GLY87

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site_id	AC8
Number of Residues	1
Details	binding site for residue IOD A 411

Chain	Residue
A	ARG270

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site_id	AC9
Number of Residues	1
Details	binding site for residue IOD A 412

Chain	Residue
A	ARG103

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site_id	AD1
Number of Residues	20
Details	binding site for residue SAH A 414

Chain	Residue
A	ASP107
A	GLY131
A	CYS132
A	GLY133
A	ASP152
A	VAL153
A	ASP179
A	MET180
A	ASN194
A	PRO196
A	LEU207
A	ILE214
A	TRS415
A	HOH524
A	HOH543
A	HOH558
A	HOH562
A	HOH568
A	HOH573
A	HOH587

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site_id	AD2
Number of Residues	9
Details	binding site for residue TRS A 415

Chain	Residue
A	ASP107
A	GLU111
A	ASN194
A	SER195
A	PRO196
A	THR197
A	LEU208
A	SAH414
A	HOH526

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