5U1Y
Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist GW791343
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0001614 | molecular_function | purinergic nucleotide receptor activity |
A | 0004931 | molecular_function | extracellularly ATP-gated monoatomic cation channel activity |
A | 0005216 | molecular_function | monoatomic ion channel activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005886 | cellular_component | plasma membrane |
A | 0006811 | biological_process | monoatomic ion transport |
A | 0016020 | cellular_component | membrane |
A | 0033198 | biological_process | response to ATP |
A | 0098655 | biological_process | monoatomic cation transmembrane transport |
Functional Information from PROSITE/UniProt
site_id | PS01212 |
Number of Residues | 27 |
Details | P2X_RECEPTOR ATP P2X receptors signature. GGiMGIeIyWdCNLDgwfhhCrPkYsF |
Chain | Residue | Details |
A | GLY249-PHE275 |