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5U1Q

Grb7-SH2 with bicyclic peptide inhibitor

Functional Information from GO Data
ChainGOidnamespacecontents
A0007165biological_processsignal transduction
B0007165biological_processsignal transduction
C0007165biological_processsignal transduction
D0007165biological_processsignal transduction
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue CL A 601
ChainResidue
AARG438
AARG458
AHOH705
LTYR5

site_idAC2
Number of Residues1
Detailsbinding site for residue CL B 601
ChainResidue
NGLY4

site_idAC3
Number of Residues4
Detailsbinding site for residue CL D 601
ChainResidue
DARG438
DARG458
DARG462
PHOH104

site_idAC4
Number of Residues1
Detailsbinding site for residue CL M 101
ChainResidue
MGLY4

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsSITE: Important for dimerization and for HRAS activation
ChainResidueDetails
AGLU488
BGLU488
CGLU488
DGLU488

227111

PDB entries from 2024-11-06

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