5U0N
Crystal structure of a methyltransferase in complex with the substrate involved in the biosynthesis of gentamicin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue SAH A 401 |
| Chain | Residue |
| A | ASP107 |
| A | MET180 |
| A | ASN194 |
| A | PRO196 |
| A | LEU207 |
| A | ILE214 |
| A | 7XP403 |
| A | HOH506 |
| A | HOH508 |
| A | HOH541 |
| A | HOH544 |
| A | GLY131 |
| A | HOH549 |
| A | HOH550 |
| A | HOH558 |
| A | HOH596 |
| A | CYS132 |
| A | GLY133 |
| A | VAL136 |
| A | ASP152 |
| A | VAL153 |
| A | GLY178 |
| A | ASP179 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | GLU98 |
| A | ASP206 |
| A | HOH509 |
| A | HOH518 |
| A | HOH525 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | binding site for residue 7XP A 403 |
| Chain | Residue |
| A | ASP95 |
| A | VAL96 |
| A | GLU97 |
| A | GLU98 |
| A | GLN101 |
| A | ASP107 |
| A | TRP110 |
| A | GLU111 |
| A | ARG176 |
| A | ASN194 |
| A | SER195 |
| A | PRO196 |
| A | THR197 |
| A | ASN198 |
| A | LEU208 |
| A | ASN235 |
| A | ARG281 |
| A | SAH401 |
| A | HOH523 |
| A | HOH538 |
| A | HOH555 |
| A | HOH571 |
