5TZE

Crystal structure of S. aureus TarS in complex with UDP-GlcNAc

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MN C 401

Chain	Residue
C	ASP93
C	ASP94
C	UD1404
C	HOH516
C	HOH522

---

site_id	AC2
Number of Residues	6
Details	binding site for residue SO4 C 402

Chain	Residue
C	ARG146
C	HOH541
C	PRO129
C	GLN130
C	SER131
C	MET132

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 C 403

Chain	Residue
C	GLN179
C	PHE221
C	SER257
C	ARG258
C	HOH519

---

site_id	AC4
Number of Residues	24
Details	binding site for residue UD1 C 404

Chain	Residue
C	PRO8
C	TYR10
C	SER12
C	ASP40
C	ASN67
C	GLY70
C	PRO71
C	PRO74
C	ARG75
C	ASP91
C	SER92
C	ASP93
C	ARG126
C	PRO153
C	LYS174
C	SER175
C	GLU177
C	ARG206
C	HIS210
C	MET211
C	SER212
C	MN401
C	HOH527
C	HOH545

---

site_id	AC5
Number of Residues	4
Details	binding site for residue MN E 401

Chain	Residue
E	ASP93
E	UD1404
E	HOH511
E	HOH550

---

site_id	AC6
Number of Residues	5
Details	binding site for residue SO4 E 402

Chain	Residue
E	PRO129
E	GLN130
E	SER131
E	MET132
E	ARG146

---

site_id	AC7
Number of Residues	4
Details	binding site for residue SO4 E 403

Chain	Residue
E	PHE221
E	SER257
E	ARG258
E	HOH504

---

site_id	AC8
Number of Residues	26
Details	binding site for residue UD1 E 404

Chain	Residue
E	PRO8
E	THR9
E	TYR10
E	SER12
E	ASP40
E	ASN67
E	GLY70
E	PRO71
E	PRO74
E	ARG75
E	ASP91
E	SER92
E	ASP93
E	SER152
E	PRO153
E	SER175
E	GLU177
E	ARG206
E	HIS210
E	MET211
E	SER212
E	MN401
E	HOH505
E	HOH511
E	HOH530
E	HOH566

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"27973583","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27973583","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27973583","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---