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5TYS

X-ray crystal structure of wild type HIV-1 protease in complex with GRL-142

Functional Information from GO Data
ChainGOidnamespacecontents
A0004190molecular_functionaspartic-type endopeptidase activity
A0006508biological_processproteolysis
B0004190molecular_functionaspartic-type endopeptidase activity
B0006508biological_processproteolysis
Functional Information from PDB Data
site_idAC1
Number of Residues26
Detailsbinding site for residue 7OA A 400
ChainResidue
AARG8
AILE50
APRO81
AVAL82
AILE84
AHOH503
BARG8
BASP25
BGLY27
BALA28
BASP29
AASP25
BASP30
BGLY48
BGLY49
BILE50
BPRO81
BVAL82
BILE84
AGLY27
AALA28
AASP29
AASP30
AILE47
AGLY48
AGLY49

Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL
ChainResidueDetails
AALA22-LEU33

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PDB entries from 2024-10-16

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